Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.52 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28033000 | 0.84 | L3MBTL1 (0.60) | PTPN1PTPN2PTPN6ABL1RIN1 | |
| SCHEMBL28822397 | 0.84 | PTPN1 (0.55) | PTPN1PTPN2PTPN6KMT2AMEN1 | |
| SCHEMBL28092176 | 0.84 | GLA (0.58) | PTPN1PTPN2PTPN6KMT2AMEN1 | |
| SCHEMBL28033418 | 0.83 | HTT (0.62) | PTPN1PTPN2PTPN6TSHRNPSR1 | |
| SCHEMBL28033057 | 0.80 | ACHE (0.53) | PTPN1PTPN2PTPN6KMT2AMEN1 | |
| SCHEMBL30182449 | 0.79 | KMT2A (0.74) | PTPN1KMT2AMEN1GAATSHR | |
| SCHEMBL30182461 | 0.79 | KMT2A (0.74) | PTPN1KMT2AMEN1GAATSHR | |
| SCHEMBL2579208 | 0.79 | KMT2A (0.74) | PTPN1KMT2AMEN1GAATSHR | |
| SCHEMBL28262980 | 0.78 | PDK2 (0.44) | KMT2ALMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL28819304 | 0.74 | RHOC (0.48) | PTPN1PTPN2PTPN6KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071490-A | Acyclic derivatives | 默克专利股份公司 | 2018-12-21 | — | — | CN | disclosed |