Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | RPA1 | P27694 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | BAD | Q92934 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6843818 | 0.84 | TP53 (0.44) | BCL2L1DHODHKDM4EMAPTNPC1 | |
| SCHEMBL6668534 | 0.83 | ALAD (0.51) | RXFP1 | |
| SCHEMBL6740513 | 0.83 | ALAD (0.51) | CA12ALPLKDM4EMAPTNPC1 | |
| SCHEMBL4553247 | 0.82 | PPARD (0.44) | MAPTADORA3MMP12 | |
| SCHEMBL15083062 | 0.81 | MAPK14 (0.43) | MAPK14DHODHKDM4EMAPTALDH1A1 | |
| SCHEMBL11000258 | 0.79 | ALPL (0.52) | ALPLKDM4EMAPTNPC1ALDH1A1 | |
| SCHEMBL12614552 | 0.78 | ADORA3 (0.37) | CA12ALPLRPA1MAPK14KDM4E | |
| SCHEMBL12614775 | 0.77 | ALDH1A1 (0.57) | MAPK14KDM4EMAPTNPC1RXFP1 | |
| SCHEMBL15083064 | 0.75 | HCAR2 (0.43) | MAPK14 | |
| SCHEMBL8605221 | 0.73 | PLK4 (0.43) | DHODHNPC1RAB9AADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105979945-A | Glucosylceramide synthase inhibitors | 建新公司 | 2016-09-28 | — | — | CN | disclosed |