Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5261760 | 0.89 | GPR84 (0.46) | P4HBMAPTLMNAKDM4EHTT | |
| SCHEMBL5260086 | 0.88 | GPR84 (0.47) | P4HBMAPTLMNAKDM4EHTT | |
| SCHEMBL28293968 | 0.82 | NR3C1 (0.61) | P4HBMAPTLMNAKDM4EHTT | |
| SCHEMBL28295738 | 0.76 | OPRL1 (0.44) | MAPTLMNAKDM4EHTTMAPK1 | |
| SCHEMBL29540078 | 0.75 | GUSB (0.61) | MAPTKMT2AMEN1NPSR1TDP1 | |
| SCHEMBL3495495 | 0.75 | GUSB (0.61) | MAPTKMT2AMEN1NPSR1TDP1 | |
| SCHEMBL6985439 | 0.75 | MAPK1 (0.48) | MAPTLMNAKDM4EHTTMAPK1 | |
| SCHEMBL9456621 | 0.75 | GPR84 (0.54) | MAPTLMNAKDM4EHTTMAPK1 | |
| SCHEMBL28295795 | 0.74 | P4HB (0.49) | P4HBMAPTKMT2AMEN1NPSR1 | |
| SCHEMBL11577771 | 0.71 | LMNA (0.44) | MAPTLMNAKDM4EHTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104016936-B | The application in efavirenz asymmetric synthesis of the chiral aminophenol part | 中国科学院上海有机化学研究所 | 2016-08-17 | — | — | CN | disclosed |