Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL352170 | 0.84 | TSHR (0.63) | TSHRTP53MAPK1HSD17B10HDAC3 | |
| Terephthalic Acid SCHEMBL9859986 | 0.84 | TSHR (0.63) | TSHRTP53MAPK1HSD17B10HDAC3 | |
| Terephthalic Acid SCHEMBL10927542 | 0.84 | TSHR (0.63) | TSHRTP53MAPK1HSD17B10HDAC3 | |
| Terephthalic Acid SCHEMBL9739994 | 0.84 | TSHR (0.63) | TSHRTP53MAPK1HSD17B10HDAC3 | |
| Terephthalic Acid SCHEMBL17727985 | 0.84 | TSHR (0.63) | TSHRTP53MAPK1HSD17B10HDAC3 | |
| Terephthalic Acid SCHEMBL869533 | 0.82 | TSHR (0.60) | TSHRTP53MAPK1HSD17B10HDAC3 | |
| Sebacic Acid SCHEMBL352890 | 0.82 | LMNA (0.60) | TSHRTP53MAPK1HSD17B10HDAC3 | |
| Terephthalic Acid SCHEMBL10528457 | 0.82 | TSHR (0.60) | TSHRTP53MAPK1HSD17B10HDAC3 | |
| Azelaic Acid SCHEMBL351913 | 0.82 | LMNA (0.60) | TSHRTP53MAPK1HSD17B10HDAC3 | |
| Terephthalic Acid SCHEMBL9850543 | 0.82 | LMNA (0.60) | TSHRTP53MAPK1HSD17B10HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105914053-A | Stretchable supercapacitor and method of manufacturing the same | 三星电子株式会社 | 2016-08-31 | — | — | CN | disclosed |