Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL9859986 | 1.00 | TSHR (0.63) | TSHRTP53LMNAHDAC3HDAC4 | |
| Terephthalic Acid SCHEMBL17727985 | 1.00 | TSHR (0.63) | TSHRTP53LMNAHDAC3HDAC4 | |
| Terephthalic Acid SCHEMBL9739994 | 1.00 | TSHR (0.63) | TSHRTP53LMNAHDAC3HDAC4 | |
| Terephthalic Acid SCHEMBL10927542 | 1.00 | TSHR (0.63) | TSHRTP53LMNAHDAC3HDAC4 | |
| Azelaic Acid SCHEMBL351913 | 0.97 | LMNA (0.60) | TSHRTP53LMNAHDAC3HDAC4 | |
| Terephthalic Acid SCHEMBL11145819 | 0.97 | LMNA (0.60) | TSHRTP53LMNAHDAC3HDAC4 | |
| Sebacic Acid SCHEMBL352890 | 0.97 | LMNA (0.60) | TSHRTP53LMNAHDAC3HDAC4 | |
| Terephthalic Acid SCHEMBL869533 | 0.97 | TSHR (0.60) | TSHRTP53LMNAHDAC3HDAC4 | |
| Sebacic Acid SCHEMBL30734379 | 0.97 | LMNA (0.60) | TSHRTP53LMNAHDAC3HDAC4 | |
| Terephthalic Acid SCHEMBL10528457 | 0.97 | TSHR (0.60) | TSHRTP53LMNAHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 614 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026055875-A9 | ONE-COMPONENT (1K) HEAT-ACTIVATABLE WATERBORNE POLYURETHANE ADHESIVE AND USE THEREOF | HENKEL AG & CO. KGAA (DE) | 2026-05-15 | — | — | WO | claimed |
| WO-2026040069-A1 | REACTIVE HOT-MELT ADHESIVE COMPOSITION AND USE THEREOF | HENKEL AG & CO. KGAA (DE) | 2026-02-26 | — | — | WO | claimed |
| CN-118852855-A | Full-biodegradation express packaging bag functional master batch and preparation method thereof | 江西轩品新材料有限公司 | 2024-10-29 | — | — | CN | claimed |
| WO-2024143770-A1 | WOOD COMPOSITE HAVING BIODEGRADABLE THERMOPLASTIC RESIN-IMPREGNATED LYOCELL CONTINUOUS FIBERS LAMINATED THEREIN | 재단법인 한국탄소산업진흥원 | 2024-07-04 | — | — | WO | claimed |
| WO-2024111836-A1 | METHOD FOR MANUFACTURING RESIN MOLDED PRODUCT USING HOT PRESS MOLDING | 주식회사 와이케이신터링 | 2024-05-30 | — | — | WO | claimed |
| CN-117736576-A | Fireproof polyamide composition and preparation method and application thereof | 江苏晋伦塑料科技有限公司 | 2024-03-22 | — | — | CN | claimed |
| WO-2023242080-A1 | LUGGAGE ITEM OR LUGGAGE ACCESSORY | Groundtruth Global Limited (GB) | 2023-12-21 | — | — | WO | claimed |
| WO-2023195747-A1 | BIODEGRADABLE COMPOSITION FOR MOLDED PRODUCT USED FOR TUBULAR MARKER | 이창훈 | 2023-10-12 | — | — | WO | claimed |
| WO-2023146018-A1 | AGRICULTURAL MULCHING VINYL HAVING EXCELLENT INSECT-REPELLENT PERFORMANCE, AND METHOD FOR MANUFACTURING SAME | 주식회사 다우테크 | 2023-08-03 | — | — | WO | claimed |
| EP-4214175-A1 | A PARTICULATE INFILL MATERIAL | Covia Europe ApS (DK) | 2023-07-26 | — | — | EP | claimed |
| CN-1946807-B | Biodegradable resin composition | TOHO CHEM IND CO LTD | 2010-10-06 | — | — | CN | claimed |
| CN-101680128-A | Thermal adhesive conjugate fiber having excellent bulkiness and softness, and fiber-molded article using same | ES FIBERVISIONS CO LTD | 2010-03-24 | — | — | CN | claimed |
| EP-1127914-B1 | Foamed starch sheet | NOVAMONT SPA (IT) | 2009-02-18 | — | — | EP | claimed |
| EP-1969940-A2 | Nematicidal compositions | Devgen NV (BE) | 2008-09-17 | — | — | EP | claimed |
| EP-1969939-A2 | Nematicidal compositions | Devgen NV (BE) | 2008-09-17 | — | — | EP | claimed |
| EP-1941798-A2 | Nematicidal compositions | Devgen NV (BE) | 2008-07-09 | — | — | EP | claimed |
| EP-1941799-A2 | Nematicidal compositions | Devgen NV (BE) | 2008-07-09 | — | — | EP | claimed |
| EP-1938691-A2 | Nematicidal compositions | Devgen NV (BE) | 2008-07-02 | — | — | EP | claimed |
| US-20080146445-A1 | Nematicidal Compositions | DEVGEN NV (BE) | 2008-06-19 | — | — | US | claimed |
| CN-1348331-A | Retarding formulations of active substances used for plant protection | BASF AG (DE) | 2002-05-08 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146445-A1 | Nematicidal Compositions | ACHE, DNPH1, NANP | TSHR 4743/4885TP53 4629/4885LMNA 2018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.