Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397704 | 0.73 | P2RX7 (0.53) | P2RX7FAAHEPHX2ALDH1A1MAPT | |
| SCHEMBL28093665 | 0.70 | P2RX7 (0.61) | P2RX7FAAHEPHX2ALDH1A1MAPT | |
| SCHEMBL28092829 | 0.67 | GAA (0.38) | P2RX7FAAHEPHX2HSD11B1ALDH1A1 | |
| SCHEMBL27839785 | 0.65 | FAAH (0.39) | P2RX7FAAHEPHX2HSD11B1ALDH1A1 | |
| SCHEMBL28091187 | 0.64 | — | — | |
| SCHEMBL3510746 | 0.64 | ALDH1A1 (0.40) | P2RX7EPHX2HSD11B1ALDH1A1MEN1 | |
| SCHEMBL13276034 | 0.62 | FAAH (0.53) | P2RX7FAAHEPHX2HSD11B1ALDH1A1 | |
| SCHEMBL7813283 | 0.62 | HSD11B1 (0.44) | P2RX7FAAHEPHX2HSD11B1ALDH1A1 | |
| SCHEMBL28094062 | 0.61 | HSD11B1 (0.55) | P2RX7EPHX2HSD11B1ALDH1A1MAPT | |
| SCHEMBL4483491 | 0.61 | NR4A2 (0.50) | P2RX7FAAHEPHX2HSD11B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106220600-A | Flavone derivatives and its production and use | 厦门大学 | 2016-12-14 | — | — | CN | disclosed |