Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MMP13 | P45452 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.55 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11900090 | 0.83 | HDAC6 (0.85) | HPGDHDAC6HDAC2HDAC8CA2 | |
| SCHEMBL6630101 | 0.83 | MAPK14 (0.68) | HPGDMAPK14RAB9ANPC1HDAC1 | |
| SCHEMBL8738317 | 0.83 | HPGD (0.97) | HPGDHDAC6HDAC2HDAC8MAPK14 | |
| SCHEMBL6140514 | 0.82 | HDAC6 (0.72) | HPGDHDAC6HDAC2HDAC8CA2 | |
| SCHEMBL2918147 | 0.81 | NPC1 (0.83) | HPGDHDAC6HDAC2HDAC8MAPK14 | |
| SCHEMBL457082 | 0.80 | HDAC6 (0.79) | HPGDHDAC6HDAC2HDAC8CA2 | |
| SCHEMBL9029700 | 0.80 | TPSAB1 (0.71) | HPGDHDAC6HDAC2HDAC8CA2 | |
| SCHEMBL6141262 | 0.79 | HPGD (0.78) | HPGDHDAC6MAPK14RAB9ALMNA | |
| SCHEMBL6798447 | 0.79 | HPGD (0.68) | HPGDHDAC6HDAC2HDAC8CA2 | |
| SCHEMBL6737728 | 0.79 | HDAC6 (0.72) | HPGDHDAC6HDAC2HDAC8CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105899496-A | OXAZOLIDINONE DERIVATIVES AS PPAR LIGANDS | 安达卢西亚健康服务部 | 2016-08-24 | — | — | CN | disclosed |