Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | CA2 | P00918 | 6/20 | 0.68 |
| ▸ | STS | P08842 | 2/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11900090 | 0.81 | HDAC6 (0.85) | HPGDCA2HDAC2HDAC8HDAC6 | |
| SCHEMBL678390 | 0.81 | CA2 (1.00) | CA2CA1LMNAALDH1A1CA12 | |
| SCHEMBL8738317 | 0.80 | HPGD (0.97) | HPGDHDAC2HDAC8HDAC6LMNA | |
| SCHEMBL28095336 | 0.79 | HPGD (0.72) | HPGDCA2HDAC2HDAC8HDAC6 | |
| SCHEMBL2918147 | 0.79 | NPC1 (0.83) | HPGDHDAC2HDAC8HDAC6LMNA | |
| SCHEMBL31530128 | 0.78 | LMNA (0.65) | HPGDCA2KDM4EPOLBTSHR | |
| SCHEMBL6793945 | 0.78 | CA2 (0.72) | CA2STSHDAC2HDAC8HDAC6 | |
| SCHEMBL457082 | 0.78 | HDAC6 (0.79) | HPGDCA2HDAC2HDAC8HDAC6 | |
| SCHEMBL6140514 | 0.77 | HDAC6 (0.72) | HPGDCA2HDAC2HDAC8HDAC6 | |
| SCHEMBL6737728 | 0.77 | HDAC6 (0.72) | HPGDCA2HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |