Formaldehyde

Formaldehyde

SCHEMBL28096113

C=O.CCCC(c1ccc(Br)cc1)c1cccs1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 4/20 0.41
HTR2A P28223 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
TDP1 Q9NUW8 2/20 0.35
CNR1 P21554 1/20 0.34
FPR2 P25090 1/20 0.33
LMNA P02545 2/20 0.33
CYP2D6 P10635 1/20 0.33
NFKB1 P19838 1/20 0.33
THPO P40225 1/20 0.33
HIF1A Q16665 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM1 P11229 1/20 0.33
DRD1 P21728 1/20 0.33
SLC6A2 P23975 1/20 0.33
HTR2C P28335 1/20 0.33
SLC6A4 P31645 1/20 0.33
HRH1 P35367 1/20 0.33
SCN1A P35498 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formaldehyde SCHEMBL28095681 0.88 CYP1A2 (0.38) SLC6A3MEN1KMT2ALMNACYP2D6
SCHEMBL28096025 0.77 SLC6A3 (0.41) SLC6A3HTR2AMEN1KMT2ACNR1
SCHEMBL7979678 0.75 HTR2A (0.48) SLC6A3HTR2AKMT2ACNR1FPR2
SCHEMBL28096112 0.74 SLC6A3 (0.39) SLC6A3HTR2AMEN1KMT2ACNR1
SCHEMBL9808852 0.73 SIGMAR1 (0.42) HTR2AHRH1
SCHEMBL921267 0.72 TAS1R3 (0.39) SLC6A3HTR2AKMT2ALMNACYP2D6
SCHEMBL4444118 0.69 ALOX5 (0.42) SLC6A3KMT2ALMNASLC6A2SLC6A4
SCHEMBL5325399 0.69 HTR2A (0.42) SLC6A3HTR2ATDP1LMNACYP2D6
SCHEMBL8091679 0.69 TAS1R3 (0.36) SLC6A3HTR2AKMT2ACYP2D6SLC6A2
SCHEMBL159474 0.68 TAS1R3 (0.37) SLC6A3HTR2AKMT2ALMNACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105924425-B A kind of method for preparing dihydro sulphur chroman derivative 浙江师范大学 2018-06-05 CN disclosed
CN-105924425-A Preparation method of dihydrothiochroman derivative 浙江师范大学 2016-09-07 CN disclosed