Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | CFD | P00746 | 3/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22544312 | 0.85 | HSD17B10 (0.53) | HSD17B10RXRARXRBGPR3HPGD | |
| SCHEMBL28107677 | 0.79 | HSD17B10 (0.44) | HSD17B10RXRARXRBGPR3HPGD | |
| SCHEMBL28107378 | 0.77 | HSD17B10 (0.46) | HSD17B10RXRARXRBGPR3HPGD | |
| SCHEMBL28107676 | 0.77 | HSD17B10 (0.46) | HSD17B10RXRARXRBGPR3HPGD | |
| SCHEMBL28107672 | 0.77 | HSD17B10 (0.46) | HSD17B10RXRARXRBGPR3HPGD | |
| SCHEMBL28319588 | 0.77 | HSD17B10 (0.46) | HSD17B10GPR3HPGDALDH1A1TOP2A | |
| SCHEMBL28107376 | 0.75 | L3MBTL1 (0.51) | HSD17B10HPGDALDH1A1BACE1KDM4E | |
| SCHEMBL28107373 | 0.75 | CYP2A6 (0.47) | HSD17B10RXRARXRBGPR3HPGD | |
| SCHEMBL883708 | 0.74 | GPR3 (0.54) | HSD17B10GPR3HPGDALDH1A1KDM4E | |
| SCHEMBL28107427 | 0.73 | HSD17B10 (0.43) | HSD17B10GPR3HPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117113-B | Polysubstituted carbazole, derivative and its synthetic method | 湘潭大学 | 2019-08-16 | — | — | CN | disclosed |
| CN-106117113-A | Polysubstituted carbazole, derivant and synthetic method thereof | 湘潭大学 | 2016-11-16 | — | — | CN | disclosed |