SCHEMBL28109693

SCHEMBL28109693

NS(=O)(=O)c1ccc(F)c(C(c2ccccc2)(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA1 P00915 12/20 0.46
CA2 P00918 12/20 0.46
CA9 Q16790 8/20 0.46
CA12 O43570 7/20 0.46
CA5A P35218 4/20 0.46
CA7 P43166 4/20 0.46
CA5B Q9Y2D0 3/20 0.46
CA4 P22748 2/20 0.46
CA6 P23280 2/20 0.46
CA14 Q9ULX7 2/20 0.46
LMNA P02545 1/20 0.43
CA13 Q8N1Q1 2/20 0.42
CA3 P07451 1/20 0.42
PLA2G7 Q13093 1/20 0.42
PTGS1 P23219 2/20 0.42
PTGS2 P35354 2/20 0.42
KIF11 P52732 1/20 0.42
SOS1 Q07889 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1497086 0.78 KIF11 (0.60) CA1CA2CA9CA12CA5A
SCHEMBL29793217 0.78 KIF11 (0.60) CA1CA2CA9CA12CA5A
SCHEMBL23633376 0.76 CA2 (0.52) CA1CA2CA9CA12CA5A
SCHEMBL28346757 0.74 CA2 (0.59) CA1CA2CA9CA12CA5A
SCHEMBL19507907 0.73 CA2 (0.49) CA1CA2CA9CA12CA5A
SCHEMBL301718 0.70 CA2 (0.69) CA1CA2CA9CA12CA5A
SCHEMBL6426040 0.70 KCNN4 (0.40) LMNAKIF11
SCHEMBL4201103 0.70 HTR6 (0.48)
SCHEMBL28298652 0.70 KCNN4 (0.37)
SCHEMBL283890 0.69 CYP3A4 (0.56) CA1CA2CA9CA12CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109851535-A A method of preparing 4- fluoro- 3- (trifyl) benzsulfamide 天津现代职业技术学院 2019-06-07 CN claimed
CN-109851535-A A method of preparing 4- fluoro- 3- (trifyl) benzsulfamide 天津现代职业技术学院 2019-06-07 CN disclosed
CN-109851535-A A method of preparing 4- fluoro- 3- (trifyl) benzsulfamide 天津现代职业技术学院 2019-06-07 CN disclosed
CN-109851535-A A method of preparing 4- fluoro- 3- (trifyl) benzsulfamide 天津现代职业技术学院 2019-06-07 CN disclosed
CN-103167867-B Solid dispersion containing apoptosis-inducing medicament ABBVIE 公司 2016-12-21 CN disclosed