Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorobenzene SCHEMBL27543512 | 0.83 | NFE2L2 (0.43) | NPC1RAB9AMEN1KMT2A | |
| Benzene SCHEMBL28131675 | 0.80 | CA2 (0.57) | CA2CA4CA5APTPN1ESR1 | |
| Toluene SCHEMBL28836845 | 0.79 | LMNA (0.52) | CA2CA4CA5AHPGDESR1 | |
| Fluorobenzene SCHEMBL28200100 | 0.78 | CA2 (0.46) | CA2CA4CA5APTPN1NPC1 | |
| Trifluoromethylbenzene SCHEMBL28841102 | 0.77 | ALDH1A1 (0.56) | PTPN1NPC1RAB9AALDH1A1CA12 | |
| Fluorobenzene SCHEMBL28905275 | 0.75 | KCNN4 (0.39) | HPGDNPC1RAB9AALDH1A1MEN1 | |
| Fluorobenzene SCHEMBL27568171 | 0.74 | — | — | |
| Fluorobenzene SCHEMBL27553303 | 0.74 | — | — | |
| Biphenyl SCHEMBL377328 | 0.72 | ACP3 (0.54) | CA2CA4CA5APTPN1ESR1 | |
| Fluorobenzene SCHEMBL27282253 | 0.72 | NFE2L2 (0.40) | HPGDNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103848868-B | method for preparing tenofovir | 蚌埠丰原涂山制药有限公司 | 2017-04-12 | — | — | CN | claimed |
| CN-103848869-B | The method preparing tenofovir | 上海医药工业研究院 | 2016-12-21 | — | — | CN | claimed |
| CN-103848868-B | method for preparing tenofovir | 蚌埠丰原涂山制药有限公司 | 2017-04-12 | — | — | CN | disclosed |
| CN-103848869-B | The method preparing tenofovir | 上海医药工业研究院 | 2016-12-21 | — | — | CN | disclosed |
| CN-103848869-B | The method preparing tenofovir | 上海医药工业研究院 | 2016-12-21 | — | — | CN | disclosed |
| CN-106146561-A | A kind of synthetic method of tenofovir | 浙江九洲药业股份有限公司 | 2016-11-23 | — | — | CN | disclosed |