SCHEMBL28113087

SCHEMBL28113087

CCc1ccccc1[N+](=O)[O-].O=C(C[N+](=O)[O-])c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
TSHR P16473 1/20 0.46
MAOB P27338 2/20 0.46
HTT P42858 2/20 0.44
MAOA P21397 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HPGD P15428 1/20 0.43
PDK1 Q15118 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
POLB P06746 2/20 0.42
CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL280150 0.82 MAPT (0.54) ALDH1A1MEN1KMT2ATSHRHTT
SCHEMBL28282184 0.81 LMNA (0.46) ALDH1A1MEN1KMT2ATSHRHTT
Hydrochloric Acid SCHEMBL27286730 0.81 MAPT (0.52) ALDH1A1MEN1KMT2ATSHRHTT
SCHEMBL124981 0.80 ALDH1A1 (0.67) ALDH1A1MEN1KMT2ATSHRMAOB
SCHEMBL29437308 0.80 ALDH1A1 (0.67) ALDH1A1MEN1KMT2ATSHRMAOB
SCHEMBL8945818 0.80 MAOA (0.59) ALDH1A1MEN1KMT2ATSHRMAOB
SCHEMBL1665800 0.79 CYP1A2 (0.51) ALDH1A1MEN1KMT2ATSHRHTT
SCHEMBL31540626 0.79 ALDH1A1 (0.64) ALDH1A1MEN1KMT2ATSHRMAOB
SCHEMBL28337088 0.78 ALDH1A1 (0.55) ALDH1A1MEN1KMT2ATSHRMAOB
Butyrophenone SCHEMBL28870598 0.78 L3MBTL1 (0.57) ALDH1A1MEN1KMT2AHTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106140147-A A kind of p nitro ethylbenzene aoxidizes p-nitroacetophenone catalyst processed and preparation method thereof 盐城工业职业技术学院 2016-11-23 CN disclosed