SCHEMBL280150

SCHEMBL280150

O=C(C[N+](=O)[O-])c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.54
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
MAPK1 P28482 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
CES1 P23141 2/20 0.54
CYP3A4 P08684 2/20 0.54
HPGD P15428 2/20 0.54
KDM4E B2RXH2 1/20 0.54
ALOX15 P16050 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
PTPN1 P18031 2/20 0.52
ERCC5 P28715 1/20 0.52
FEN1 P39748 1/20 0.52
ALDH1A1 P00352 5/20 0.50
GSK3B P49841 2/20 0.50
HIF1A Q16665 2/20 0.50
TRPA1 O75762 1/20 0.50
L3MBTL1 Q9Y468 3/20 0.48
LMNA P02545 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27286730 0.98 MAPT (0.52) MAPTMEN1KMT2AMAPK1TDP1
Acetohydroxamic Acid SCHEMBL28871685 0.88 MEN1 (0.47) MAPTMEN1KMT2AMAPK1TDP1
Butyrophenone SCHEMBL28870598 0.88 L3MBTL1 (0.57) MAPTMEN1KMT2AMAPK1TDP1
SCHEMBL5682430 0.84 MEN1 (0.57) MAPTMEN1KMT2AMAPK1TDP1
SCHEMBL8779987 0.84 ERCC5 (0.61) MAPTMEN1KMT2AMAPK1ERCC5
SCHEMBL11756446 0.83 TP53 (0.56) MAPTKDM4ENPC1RAB9A
SCHEMBL28113087 0.82 ALDH1A1 (0.50) MAPTMEN1KMT2AHPGDSMN1; SMN2
SCHEMBL27858771 0.81 PTPN1 (0.52) MAPTTDP1HPGDKDM4EPTPN1
SCHEMBL6739488 0.81 CES2 (0.55) MAPTCES1SMN1; SMN2ALDH1A1LMNA
SCHEMBL6782133 0.79 NPC1 (0.53) MAPTMEN1KMT2ACES1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1551 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116262673-B Preparation method of alpha-bromoacetophenone compound 浙江工业大学 2025-04-29 CN claimed
CN-119650304-A Electrolyte, preparation method thereof and aluminum electrolytic capacitor 东莞东阳光科研发有限公司 2025-03-18 CN claimed
CN-119626782-A Core of aluminum electrolytic capacitor and aluminum electrolytic capacitor comprising same 珠海格力新元电子有限公司 2025-03-14 CN claimed
CN-119318957-A For synthesizing photosensitivity catalyst for diamine compound 青岛伯川特聚科技有限公司 2025-01-17 CN claimed
CN-117820129-B Method for preparing corresponding aromatic amine by selective hydrogenation of photocatalytic aromatic nitro compound 南京先进生物材料与过程装备研究院有限公司 2024-09-06 CN claimed
CN-114678220-B Soldering lug type aluminum electrolytic capacitor 珠海格力新元电子有限公司 2024-09-06 CN claimed
CN-116284758-B Intrinsic antibacterial nylon and preparation method and application thereof 桂林理工大学 2024-08-27 CN claimed
CN-117820129-A Method for preparing corresponding aromatic amine by selective hydrogenation of photocatalytic aromatic nitro compound 南京先进生物材料与过程装备研究院有限公司 2024-04-05 CN claimed
CN-117659906-A Packaging adhesive film composition, packaging adhesive film and application 福斯特(滁州)新材料有限公司 2024-03-08 CN claimed
CN-113735712-B Preparation method of o-nitrobenzaldehyde 迈奇化学股份有限公司 2024-03-08 CN claimed
EP-0347488-B1 Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof AMERICAN CYANAMID CO (US) 1994-06-01 EP claimed
EP-0347488-A1 Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof AMERICAN CYANAMID COMPANY (US) 1989-12-27 EP claimed
US-4857651-A α-(2,3-Di(C1 -C4 alkoxy)ethylamino)-β-cyanostyrene and β-nitrostyrene compounds useful as intermediates in the preparation of insecticidal, acaricidal and nematicidal arylpyrroles and method for the preparation thereof AMERICAN CYANAMID COMPANY (US) 1989-08-15 US claimed
US-4352942-A TREATMENT OF ISOMERIC MIXTURE OF NITRO AROMATIC KETO COMPOUNDS WITH OLEUM GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-10-05 US claimed
US-4169853-A HYDROGENATION, CATALYST SELECTIVITY TEXACO DEVELOPMENT CORPORATION (US) 1979-10-02 US claimed
US-4103086-A 8-Oxo-4-thia-1-azabicyclo (4.2.0)-oct-2-ene derivatives SMITHKLINE CORPORATION (US) 1978-07-25 US claimed
US-4092327-A Preparation of isoxazolines TEXACO INC. (US) 1978-05-30 US claimed
US-4089867-A Preparation of diacylfurazan oxides TEXACO INC. (US) 1978-05-16 US claimed
US-4061651-A Preparation of 3,5-disubstituted-4-nitroisoxazoles TEXACO INC. (US) 1977-12-06 US claimed
US-4000154-A 3-Substituted-6β-(amino- and acylamino)-7-oxo-1,3-diazabicyclo[3.2.0]-h SMITHKLINE CORPORATION (US) 1976-12-28 US claimed