Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.50 |
| ▸ | HTR3B | O95264 | 2/20 | 0.50 |
| ▸ | HTR3A | P46098 | 2/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.50 |
| ▸ | XDH | P47989 | 2/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167824 | 0.92 | GAA (0.55) | CTBP2GAAGRIN2BHTR3EHTR3B | |
| SCHEMBL6167827 | 0.92 | GAA (0.55) | CTBP2GAAGRIN2BHTR3EHTR3B | |
| SCHEMBL4586154 | 0.83 | CTSL (0.55) | CTBP2XDHNLRP3CTSLSMN1; SMN2 | |
| SCHEMBL257218 | 0.83 | CTSL (0.55) | CTBP2XDHNLRP3CTSLSMN1; SMN2 | |
| SCHEMBL4586157 | 0.83 | CTSL (0.55) | CTBP2XDHNLRP3CTSLSMN1; SMN2 | |
| SCHEMBL28303420 | 0.82 | CTBP2 (0.51) | CTBP2GRIN2BXDHNLRP3CTSL | |
| SCHEMBL28487187 | 0.82 | L3MBTL1 (0.58) | CTBP2GRIN2BXDHNLRP3CTSL | |
| SCHEMBL29509890 | 0.81 | XDH (0.47) | XDHCTSLALDH1A1MAPTKDM4E | |
| SCHEMBL28232897 | 0.81 | XDH (0.47) | XDHCTSLALDH1A1MAPTKDM4E | |
| SCHEMBL10666772 | 0.78 | CTBP2 (0.61) | CTBP2SIGMAR1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146350-B | A kind of new method of synthesizing amino formic acid oxime ester derivative | 华南理工大学 | 2017-10-20 | — | — | CN | claimed |
| CN-106146350-A | A kind of new method of synthesizing amino methylcarbamoyl oximino ester derivant | 华南理工大学 | 2016-11-23 | — | — | CN | claimed |