Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28837064 | 0.88 | L3MBTL1 (0.51) | L3MBTL1MEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL28115348 | 0.86 | L3MBTL1 (0.55) | L3MBTL1MEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL8356932 | 0.76 | LMNA (0.73) | ALDH1A1MAPTLMNAKDM4ERAB9A | |
| SCHEMBL13762897 | 0.73 | CHRM1 (0.77) | TP53ALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL1994563 | 0.73 | ADRA1D (0.54) | TP53ALDH1A1MAPTLMNAPDE4B | |
| SCHEMBL28114857 | 0.71 | MYC (0.51) | L3MBTL1KMT2ALMNARECQLMYC | |
| SCHEMBL30589589 | 0.71 | ALDH1A1 (0.57) | MEN1KMT2ATP53ALDH1A1MAPT | |
| SCHEMBL13931038 | 0.70 | NPSR1 (0.59) | L3MBTL1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL30589586 | 0.70 | MAPT (0.55) | MEN1KMT2ATP53ALDH1A1MAPT | |
| SCHEMBL27707835 | 0.69 | MAPT (0.65) | L3MBTL1MEN1KMT2ATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106243012-A | New indole analog derivative and preparation method thereof | 北方民族大学 | 2016-12-21 | — | — | CN | disclosed |