Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ERN1 | O75460 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28114852 | 0.86 | L3MBTL1 (0.56) | L3MBTL1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28837064 | 0.82 | L3MBTL1 (0.51) | L3MBTL1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9733117 | 0.76 | ALDH1A1 (0.67) | L3MBTL1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL31428978 | 0.75 | ALDH1A1 (0.58) | ERN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL9584018 | 0.73 | PLA2G2A (0.61) | ALDH1A1LMNABCHE | |
| SCHEMBL28530692 | 0.72 | ABCC2 (0.60) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28477087 | 0.72 | BCHE (0.55) | ALDH1A1MAPTLMNASMN1; SMN2BCHE | |
| SCHEMBL2161419 | 0.71 | CNR2 (0.56) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL28407940 | 0.70 | BCHE (0.46) | BCHE | |
| SCHEMBL27707835 | 0.69 | MAPT (0.65) | L3MBTL1MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106243012-A | New indole analog derivative and preparation method thereof | 北方民族大学 | 2016-12-21 | — | — | CN | disclosed |