Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28115023 | 0.87 | MAPT (0.46) | POLBMAPTKDM4ELMNACCR6 | |
| SCHEMBL28115569 | 0.85 | KDM4E (0.50) | MAPTTP53KDM4ELMNAACACA | |
| SCHEMBL28115474 | 0.82 | MAPT (0.60) | POLBMAPTTP53KDM4ELMNA | |
| SCHEMBL28837021 | 0.82 | MAPT (0.60) | POLBMAPTTP53KDM4ELMNA | |
| SCHEMBL28115475 | 0.78 | MAPT (0.45) | POLBMAPTTP53KDM4ELMNA | |
| SCHEMBL28115074 | 0.76 | DHODH (0.54) | POLBMAPTKDM4EHTTALDH1A1 | |
| SCHEMBL28115022 | 0.76 | DHODH (0.53) | MAPTTP53KDM4EACACAALDH1A1 | |
| SCHEMBL28115477 | 0.76 | RXFP1 (0.52) | POLBMAPTTP53KDM4ELMNA | |
| SCHEMBL28115083 | 0.76 | MAPT (0.48) | MAPTTP53KDM4ELMNAALDH1A1 | |
| SCHEMBL28118267 | 0.75 | KDM4E (0.43) | POLBMAPTTP53KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106220560-A | A kind of preparation method of poly-substituted quinoline derivant | 华侨大学 | 2016-12-14 | — | — | CN | disclosed |