Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28115569 | 0.90 | KDM4E (0.50) | MAPTTP53LMNAALDH1A1ACACA | |
| SCHEMBL28115477 | 0.88 | RXFP1 (0.52) | MAPTTP53POLBLMNAALDH1A1 | |
| SCHEMBL28115474 | 0.82 | MAPT (0.60) | MAPTTP53POLBLMNAALDH1A1 | |
| SCHEMBL28837021 | 0.80 | MAPT (0.60) | MAPTTP53POLBLMNAALDH1A1 | |
| SCHEMBL28115074 | 0.79 | DHODH (0.54) | MAPTPOLBALDH1A1KDM4EGAA | |
| SCHEMBL28115022 | 0.79 | DHODH (0.53) | MAPTTP53ALDH1A1ACACAKDM4E | |
| SCHEMBL28115476 | 0.78 | POLB (0.57) | MAPTTP53POLBLMNAALDH1A1 | |
| SCHEMBL28115023 | 0.78 | MAPT (0.46) | MAPTPOLBLMNAALDH1A1MCL1 | |
| SCHEMBL10671292 | 0.76 | PDE10A (0.58) | POLBLMNAACACAKDM4ESMN1; SMN2 | |
| SCHEMBL28837077 | 0.76 | TRPV1 (0.43) | MAPTLMNAALDH1A1KDM4EDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106220560-A | A kind of preparation method of poly-substituted quinoline derivant | 华侨大学 | 2016-12-14 | — | — | CN | disclosed |