Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28115476 | 0.87 | POLB (0.57) | MAPTPOLBKDM4ELMNAMEN1 | |
| SCHEMBL28115569 | 0.85 | KDM4E (0.50) | MAPTKDM4ELMNACYP1A2CYP3A4 | |
| SCHEMBL28115022 | 0.81 | DHODH (0.53) | MAPTKDM4ECYP2C9ALDH1A1ACACA | |
| SCHEMBL28115475 | 0.78 | MAPT (0.45) | MAPTPOLBKDM4ELMNACYP1A2 | |
| SCHEMBL28837021 | 0.77 | MAPT (0.60) | MAPTPOLBKDM4ELMNANPSR1 | |
| SCHEMBL28115474 | 0.77 | MAPT (0.60) | MAPTPOLBKDM4ELMNACYP3A4 | |
| SCHEMBL28115477 | 0.76 | RXFP1 (0.52) | MAPTPOLBKDM4ELMNACYP2C9 | |
| SCHEMBL28115074 | 0.76 | DHODH (0.54) | MAPTPOLBKDM4ENPSR1MEN1 | |
| SCHEMBL28121888 | 0.76 | PLAAT3 (0.48) | MAPTMEN1KMT2AALDH1A1PPARA | |
| SCHEMBL28837077 | 0.74 | TRPV1 (0.43) | MAPTKDM4ELMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106220560-A | A kind of preparation method of poly-substituted quinoline derivant | 华侨大学 | 2016-12-14 | — | — | CN | disclosed |