Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KYNU | Q16719 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2208871 | 0.88 | SRC (0.50) | SRCMAPTPKMGAAALPI | |
| SCHEMBL869693 | 0.80 | ALDH1A1 (0.47) | SRCMAPTPKMGAAPTGS1 | |
| SCHEMBL21753694 | 0.77 | ALOX15 (0.41) | SRCMAPTGAAALDH1A1KYNU | |
| SCHEMBL23581315 | 0.77 | SRC (0.43) | SRCMAPTALDH1A1MEN1CRHBP | |
| SCHEMBL8209123 | 0.77 | CES2 (0.44) | SRCGAAMEN1KMT2ALMNA | |
| SCHEMBL29741549 | 0.77 | SRC (0.43) | SRCMAPTALDH1A1MEN1CRHBP | |
| SCHEMBL8209137 | 0.77 | CXCL8 (0.44) | SRCMAPTGAAALDH1A1MEN1 | |
| SCHEMBL5982890 | 0.76 | LMNA (0.40) | SRCSLC7A5ALDH1A1KYNUCFTR | |
| SCHEMBL24355546 | 0.76 | CA1 (0.39) | MAPTGAAALDH1A1KDM4ECFTR | |
| SCHEMBL24355543 | 0.76 | CA1 (0.39) | MAPTGAAALDH1A1KDM4ECFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106278925-B | A kind of preparation method of Antirheumatic Drug Actarit | 平光制药股份有限公司 | 2019-01-25 | — | — | CN | disclosed |
| CN-106278925-A | A kind of preparation method of Antirheumatic Drug Actarit | 平光制药股份有限公司 | 2017-01-04 | — | — | CN | disclosed |