Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27856092 | 0.80 | MYC (0.34) | MYCNR4A1HSD17B3 | |
| SCHEMBL28121191 | 0.78 | BCHE (0.37) | — | |
| SCHEMBL26654402 | 0.63 | PTPN1 (0.36) | — | |
| SCHEMBL14469037 | 0.60 | ERN1 (0.33) | — | |
| SCHEMBL28094908 | 0.60 | GRIA1 (0.39) | MYCNR4A1HSD17B3 | |
| SCHEMBL28814496 | 0.60 | MEN1 (0.35) | MYCNR4A1CYP2A6 | |
| SCHEMBL27704528 | 0.58 | TGM2 (0.40) | CYP2A6 | |
| SCHEMBL2495874 | 0.58 | NOX1 (0.52) | HSD17B3 | |
| SCHEMBL19897160 | 0.57 | DRD2 (0.36) | HSD17B3 | |
| SCHEMBL14469112 | 0.57 | RAB9A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459027-B | 6-substituted-3H-1, 3-benzothiazol-2-one compounds as TARP-gamma 8 dependent AMPA receptor antagonists | 伊莱利利公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-106459027-A | 6-substituted-3H-1, 3-benzothiazol-2-one compounds as TARP-gamma 8 dependent AMPA receptor antagonists | 伊莱利利公司 | 2017-02-22 | — | — | CN | disclosed |