Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.60 |
| ▸ | ITGA1 | P56199 | 4/20 | 0.59 |
| ▸ | PPARG | P37231 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CDK7 | P50613 | 1/20 | 0.47 |
| ▸ | CCNH | P51946 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94831 | 0.81 | MAPT (0.63) | HDAC1HDAC8MAPTLMNAMEN1 | |
| SCHEMBL28121241 | 0.81 | MAPT (0.63) | HDAC1HDAC8MAPTLMNAMEN1 | |
| SCHEMBL14018772 | 0.81 | MAPT (0.63) | HDAC1HDAC8MAPTLMNAMEN1 | |
| SCHEMBL7577795 | 0.81 | ITGA1 (0.74) | HDAC1HDAC8MAPTLMNAMEN1 | |
| SCHEMBL5020767 | 0.80 | HDAC1 (0.78) | HDAC1HDAC8MAPTLMNAMEN1 | |
| SCHEMBL5020625 | 0.80 | HDAC1 (1.00) | HDAC1HDAC8MAPTLMNAMEN1 | |
| SCHEMBL3268657 | 0.80 | MAPT (0.61) | HDAC1HDAC8MAPTLMNAMEN1 | |
| SCHEMBL3267775 | 0.79 | PPARG (0.52) | HDAC1HDAC8MAPTLMNAMEN1 | |
| SCHEMBL4882914 | 0.79 | PGR (0.61) | HDAC1HDAC8MAPTLMNAMEN1 | |
| SCHEMBL3267231 | 0.78 | ITGA1 (0.61) | HDAC1HDAC8MAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1914229-B1 | NOVEL CERCOSPORAMIDE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2010-06-16 | — | — | EP | disclosed |
| US-20090036492-A1 | Novel Cercosporamide Derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1914229-A1 | NOVEL CERCOSPORAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036492-A1 | Novel Cercosporamide Derivative | GPR119, CBR3, SLC5A2 | HDAC1 765/4885HDAC8 1099/4885MAPT 4836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.