Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP7 | O15540 | 1/20 | 0.41 |
| ▸ | FABP3 | P05413 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.33 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21444063 | 0.81 | GAA (0.46) | ATMTDP1MAPTALDH1A1KMT2A | |
| SCHEMBL27581710 | 0.81 | L3MBTL1 (0.43) | ATMTDP1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL7994148 | 0.81 | TDP1 (0.45) | ATMTDP1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL16672909 | 0.81 | POLB (0.47) | ATMMAPTALDH1A1L3MBTL1MEN1 | |
| SCHEMBL2140678 | 0.80 | ELANE (0.49) | FABP7FABP3FABP5ATMTDP1 | |
| SCHEMBL29435434 | 0.80 | ELANE (0.46) | FABP7FABP3FABP5ATMTDP1 | |
| SCHEMBL4246889 | 0.80 | ELANE (0.46) | FABP7FABP3FABP5ATMTDP1 | |
| SCHEMBL16672824 | 0.79 | L3MBTL1 (0.54) | MAPTALDH1A1L3MBTL1GLAKMT2A | |
| SCHEMBL27844909 | 0.79 | ALDH1A1 (0.47) | ATMTDP1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL28330441 | 0.77 | THRA (0.50) | THRBTHRANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484500-A | A kind of preparation method of 1- trifluoroethyls isoquinolin | 四川理工学院 | 2018-09-04 | — | — | CN | disclosed |
| CN-106543081-A | A kind of preparation method of 1 fluoroalkyl isoquinolin | 四川理工学院 | 2017-03-29 | — | — | CN | disclosed |