Triphosphate

Triphosphate

SCHEMBL28137708

Cc1cc2cccnc2[nH]1.O=P(O)(O)OP(=O)(O)OP(=O)(O)O

nearest known ligand 0.46

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.46
RIPK1 Q13546 13/20 0.43
VCP P55072 1/20 0.41
CCNB2 O95067 1/20 0.41
CDK1 P06493 1/20 0.41
CCNB1 P14635 1/20 0.41
CCNB3 Q8WWL7 1/20 0.41
HRH4 Q9H3N8 1/20 0.40
HRH3 Q9Y5N1 1/20 0.40
MAP3K5 Q99683 1/20 0.39
CCNE1 P24864 1/20 0.38
CDK2 P24941 1/20 0.38
CNR2 P34972 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12333 0.82 DAO (0.53) DAORIPK1CCNB2CDK1CCNB1
Triphosphate SCHEMBL27542524 0.71 ALDH1A1 (0.59)
SCHEMBL28193975 0.71 FDPS (0.41)
Phosphoric Acid SCHEMBL28527815 0.70 RIPK1 (0.50) DAORIPK1CCNB2CDK1CCNB1
SCHEMBL28135193 0.70 DAO (0.42) DAORIPK1CCNB2CDK1CCNB1
SCHEMBL14281536 0.66 KDM4E (0.53) DAOVCP
SCHEMBL435130 0.66 DAO (0.65) DAORIPK1CCNB2CDK1CCNB1
SCHEMBL29756947 0.66 DAO (0.65) DAORIPK1CCNB2CDK1CCNB1
SCHEMBL4271585 0.66 HRH4 (0.57) DAORIPK1CCNB2CDK1CCNB1
SCHEMBL31088687 0.66 HRH4 (0.57) DAORIPK1CCNB2CDK1CCNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108778477-A Bifurcated mixer and methods of use and manufacture thereof 不列颠哥伦比亚大学 2018-11-09 CN disclosed
CN-107921381-A Disposable micro-fluidic box 不列颠哥伦比亚大学 2018-04-17 CN disclosed
CN-107028886-A Lipid particle and related methods containing nucleic acid 不列颠哥伦比亚大学 2017-08-11 CN disclosed
CN-102712935-B Nucleic acid-containing lipid particles and related methods 不列颠哥伦比亚大学 2017-04-26 CN disclosed
CN-105813721-A Device for dispensing particles in small volumes 不列颠哥伦比亚大学 2016-07-27 CN disclosed
CN-105143456-A Lipid nanoparticles for transfection and related methods UNIV BRITISH COLUMBIA 2015-12-09 CN disclosed
CN-102712935-A Nucleic acid-containing lipid particles and related methods UNIV BRITISH COLUMBIA 2012-10-03 CN disclosed