SCHEMBL12333

SCHEMBL12333

Cc1cc2cccnc2[nH]1

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.53
RIPK1 Q13546 13/20 0.50
CCNB2 O95067 1/20 0.50
CDK1 P06493 1/20 0.50
CCNB1 P14635 1/20 0.50
CCNB3 Q8WWL7 1/20 0.50
MAPT P10636 1/20 0.46
SNCA P37840 1/20 0.46
AXL P30530 1/20 0.45
NUDT1 P36639 1/20 0.45
HRH4 Q9H3N8 1/20 0.44
HRH3 Q9Y5N1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28135193 0.85 DAO (0.42) DAORIPK1CCNB2CDK1CCNB1
Triphosphate SCHEMBL28137708 0.82 DAO (0.46) DAORIPK1CCNB2CDK1CCNB1
SCHEMBL1781693 0.79 RIPK1 (0.50) DAORIPK1CCNB2CDK1CCNB1
SCHEMBL29756947 0.77 DAO (0.65) DAORIPK1CCNB2CDK1CCNB1
SCHEMBL435130 0.77 DAO (0.65) DAORIPK1CCNB2CDK1CCNB1
SCHEMBL24103159 0.76 DAO (0.50) DAORIPK1CCNB2CDK1CCNB1
SCHEMBL2595303 0.75 DAO (0.53) DAORIPK1CCNB2CDK1CCNB1
SCHEMBL575029 0.75 DAO (0.53) DAORIPK1CCNB2CDK1CCNB1
SCHEMBL30678374 0.75 DAO (0.62) DAORIPK1CCNB2CDK1CCNB1
SCHEMBL745278 0.75 DAO (0.53) DAORIPK1CCNB2CDK1CCNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 420 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110343104-A A kind of synthetic method of 2- methyl -7- azaindole 陈建江 2019-10-18 CN claimed
CN-102827162-A Preparation method of 2-methyl-7-azaindole ABA CHEMICALS SHANGHAI LTD 2012-12-19 CN claimed
CN-122010905-A Pyrazolyl derivatives as anticancer agents 诺华股份有限公司 2026-05-12 CN disclosed
US-12590071-B2 Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2026-03-31 US disclosed
US-12577243-B2 Monoacylglycerol lipase modulators JANSSEN PHARMACEUTICA NV (BE) 2026-03-17 US disclosed
EP-4344702-B1 PYRAZOLYL DERIVATIVES USEFUL AS ANTI-CANCER AGENTS NOVARTIS AG (CH) 2026-01-28 EP disclosed
US-20250346922-A1 COMPOUNDS FOR IMPROVEMENT OF VIRAL PRODUCTION TENAYA THERAPEUTICS INC (US) 2025-11-13 US disclosed
WO-2025226545-A1 MODULATORS OF MITOCHONDRIAL DNA REPLICATION PRETZEL THERAPEUTICS, INC. (US) 2025-10-30 WO disclosed
US-20250243196-A1 CITRON KINASE INHIBITORS THE CLEVELAND CLINIC FOUNDATION 2025-07-31 US disclosed
US-20250230157-A1 AZABENZIMIDAZOLES AND THEIR USE AS AMPA RECEPTOR MODULATORS RAPPORT THERAPEUTICS, INC. 2025-07-17 US disclosed
US-12201617-B2 HDAC6 inhibitors for treatment of metabolic disease and HFpEF TENAYA THERAPEUTICS, INC. (US) 2025-01-21 US disclosed
US-6312835-B1 ALUMINUM AND BORON COMPLEXES OF 7-AZAINDOLES AND ALUMINUM COMPLEXES OF DI-2-PYRIDYLAMINES AND N-PHENYL-2-PYRIDYLAMINES QUEEN'S UNIVERSITY AT KINGSTON (CA) 2001-11-06 US disclosed
EP-0509974-B1 Pyrrolo[2,3-b]pyridines having therapeutic activity and a process for the preparation thereof ASTRA AB (SE) 1999-01-13 EP disclosed
WO-1998036035-A1 LUMINESCENT COMPOUNDS AND METHODS OF MAKING AND USING SAME QUEEN'S UNIVERSITY AT KINGSTON (CA) 1998-08-20 WO disclosed
US-5681959-A DEPROTONATION OF A 2-AMINO-3-ALKYLPYRIDINE WITH AN ALKYLLITHIUM COMPOUND, THEN REACTION WITH AN AMIDE OR ESTER AND TREATMENT WITH A CONCENTRATED ACID FOR CYCLIZATION MERCK, SHARP & DOHME LTD. (GB) 1997-10-28 US disclosed
US-5439917-A Phenyl-pyrrolo(2,3-b)pyridine antisecretory agent of gastric acid; adenosine triphosphatase enzyme inhibitor AKTIEBOLAGET ASTRA (SE) 1995-08-08 US disclosed
EP-0580616-A1 NEW ACTIVE COMPOUNDS Astra Aktiebolag (SE) 1994-02-02 EP disclosed
CN-1067892-A The preparation method of new pyrrolo-[2,3-b] pyridine derivate ASTRA AB (SE) 1993-01-13 CN disclosed
EP-0509974-A1 Pyrrolo[2,3-b]pyridines having therapeutic activity and a process for the preparation thereof Astra Aktiebolag (SE) 1992-10-21 EP disclosed
WO-1992017477-A1 NEW ACTIVE COMPOUNDS AKTIEBOLAGET ASTRA (SE) 1992-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577243-B2 Monoacylglycerol lipase modulators MGLL, LPL, FAAH DAO 1421/4885RIPK1 3954/4885CCNB2 4568/4885
US-12201617-B2 HDAC6 inhibitors for treatment of metabolic disease and HFpEF HDAC6, HDAC1, HDAC2 DAO 2175/4885RIPK1 3160/4885CCNB2 4711/4885
US-20250243196-A1 CITRON KINASE INHIBITORS CHEK2, CILK1, DCK DAO 3378/4885RIPK1 483/4885CCNB2 1118/4885
US-12590071-B2 Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof ABL1, TH, CYP3A43 DAO 213/4885RIPK1 2670/4885CCNB2 4476/4885
US-20250230157-A1 AZABENZIMIDAZOLES AND THEIR USE AS AMPA RECEPTOR MODULATORS GRIN1, GRIN2B, GRIN3A DAO 587/4885RIPK1 2340/4885CCNB2 2360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.