Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28201427 | 0.85 | TSHR (0.40) | TSHRTHRB | |
| SCHEMBL140890 | 0.84 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL16538074 | 0.80 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL26918864 | 0.79 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL21101830 | 0.79 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL16537404 | 0.79 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL29402140 | 0.79 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL1024881 | 0.77 | TSHR (0.43) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL138700 | 0.76 | TSHR (0.54) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL733860 | 0.76 | TSHR (0.47) | TSHRHPGDALDH1A1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189685-B | Method for forming thermally conductive thermal radical cure silicone composition | 道康宁公司 | 2017-08-08 | — | — | CN | disclosed |
| CN-104968751-B | Curable silicone compositions comprising clustured functional polyorganosiloxanes and silicone reactive diluents | 道康宁公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-104968750-B | Clustered functional polyorganosiloxanes, processes for forming same and methods for their use | 道康宁公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-104968749-B | Stability hot radical curable organosilicon adhesive composition | 道康宁公司 | 2017-03-29 | — | — | CN | disclosed |