Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | GABRP | O00591 | 2/20 | 0.48 |
| ▸ | GABRD | O14764 | 2/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.48 |
| ▸ | GABRE | P78334 | 2/20 | 0.48 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.48 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.48 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.48 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2807685 | 0.98 | KDM4E (0.50) | KDM4EKMT2ATDP1MEN1GABRP | |
| SCHEMBL2810184 | 0.98 | KDM4E (0.50) | KDM4EKMT2ATDP1MEN1GABRP | |
| SCHEMBL274410 | 0.88 | GABRP (0.52) | KDM4EKMT2ATDP1MEN1GABRP | |
| SCHEMBL30280663 | 0.88 | GABRP (0.52) | KDM4EKMT2ATDP1MEN1GABRP | |
| SCHEMBL13365081 | 0.88 | KDM4E (0.50) | KDM4EKMT2ATDP1MEN1GABRP | |
| SCHEMBL28347494 | 0.88 | KDM4E (0.50) | KDM4EKMT2ATDP1MEN1GABRP | |
| SCHEMBL4732592 | 0.88 | GABRP (0.52) | KDM4EKMT2ATDP1MEN1GABRP | |
| SCHEMBL2811742 | 0.87 | GLA (0.45) | KDM4EKMT2ATDP1MEN1GABRP | |
| SCHEMBL2811740 | 0.87 | GLA (0.45) | KDM4EKMT2ATDP1MEN1GABRP | |
| SCHEMBL12398857 | 0.85 | GRM1 (0.51) | KDM4EKMT2ATDP1MEN1GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3426246-B1 | THIAZOLIDINONE COMPOUNDS AND USE THEREOF | NATIONAL HEALTH RES INST (TW) | 2024-05-01 | — | — | EP | disclosed |
| US-20230036854-A1 | HETEROCYCLIC SPIRO-COMPOUNDS AS AM2 RECEPTOR INHIBITORS | THE UNIVERSITY OF SHEFFIELD (GB) | 2023-02-02 | — | — | US | disclosed |
| CN-114007695-A | As AM2Heterocyclic spiro-compounds as receptor inhibitors | 谢菲尔德大学 | 2022-02-01 | — | — | CN | disclosed |
| EP-3880308-A1 | HETEROCYCLIC SPIRO-COMPOUNDS AS AM2 RECEPTOR INHIBITORS | The University Of Sheffield (GB) | 2021-09-22 | — | — | EP | disclosed |
| WO-2020099885-A1 | HETEROCYCLIC SPIRO-COMPOUNDS AS AM2 RECEPTOR INHIBITORS | THE UNIVERSITY OF SHEFFIELD (GB) | 2020-05-22 | — | — | WO | disclosed |
| US-10544113-B2 | Thiazolidinone compounds and use thereof | NATIONAL HEALTH RESEARCH INSTITUTE (TW) | 2020-01-28 | — | — | US | disclosed |
| EP-3426246-A1 | THIAZOLIDINONE COMPOUNDS AND USE THEREOF | National Health Research Institutes (TW) | 2019-01-16 | — | — | EP | disclosed |
| WO-2017155910-A1 | THIAZOLIDINONE COMPOUNDS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2017-09-14 | — | — | WO | disclosed |
| US-20170253569-A1 | THIAZOLIDINONE COMPOUNDS AND USE THEREOF | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2017-09-07 | — | — | US | disclosed |
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | FUJIFILM CORPORATION (JP) | 2010-11-11 | — | — | US | disclosed |
| EP-0133533-B1 | Low thermal expansion resin material for a wiring insulating film. | HITACHI, LTD. (JP) | 1993-04-21 | — | — | EP | disclosed |
| EP-0499986-A2 | Multilayer wiring structure and method for forming multilayer construction | HITACHI, LTD. (JP) | 1992-08-26 | — | — | EP | disclosed |
| US-5133989-A | PROCESS FOR PRODUCING METAL-POLYIMIDE COMPOSITE ARTICLE | HITACHI, LTD. (JP) | 1992-07-28 | — | — | US | disclosed |
| US-5120573-A | PROCESS FOR PRODUCING METAL/POLYIMIDE COMPOSITE ARTICLE | HITACHI, LTD. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0389195-A2 | A process of forming a patterned polyimide film and articles including such a film | HITACHI, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |
| EP-0361462-A2 | Process for producing copper or silver/polyimide composite article | HITACHI, LTD. (JP) | 1990-04-04 | — | — | EP | disclosed |
| EP-0361461-A2 | Process for producing metal-polyimide composite article | HITACHI, LTD. (JP) | 1990-04-04 | — | — | EP | disclosed |
| US-4792476-A | AROMATIC POLYIMIDES | HITACHI, LTD. (JP) | 1988-12-20 | — | — | US | disclosed |
| US-4690999-A | MOLECULARLY-ORIENTED POLYIMIDES BASED ON PARA-AROMATIC DIAMINES; FILMS; PROTECTIVE COATINGS; INTEGRATED CIRCUITS | HITACHI, LTD. (JP) | 1987-09-01 | — | — | US | disclosed |
| EP-0133533-A2 | Low thermal expansion resin material for a wiring insulating film. | HITACHI, LTD. (JP) | 1985-02-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544113-B2 | Thiazolidinone compounds and use thereof | OPRL1, OPRD1, OPRK1 | KDM4E 3848/4885KMT2A 3536/4885TDP1 3865/4885 |
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | KAT8, HDAC10, SSRP1 | KDM4E 3239/4885KMT2A 583/4885TDP1 4001/4885 |
| US-20230036854-A1 | HETEROCYCLIC SPIRO-COMPOUNDS AS AM2 RECEPTOR INHIBITORS | MC2R, AGTR2, NR3C2 | KDM4E 4724/4885KMT2A 3866/4885TDP1 4742/4885 |
| US-20170253569-A1 | THIAZOLIDINONE COMPOUNDS AND USE THEREOF | OPRL1, OPRD1, OPRK1 | KDM4E 3848/4885KMT2A 3536/4885TDP1 3865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.