Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16675402 | 0.91 | SMN1; SMN2 (0.57) | SMN1; SMN2ATMALDH1A1MAPTHPGD | |
| SCHEMBL1814868 | 0.82 | SMN1; SMN2 (0.61) | SMN1; SMN2ATMALDH1A1MAPTHPGD | |
| SCHEMBL9490926 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1MAPTHPGDMPI | |
| SCHEMBL8971624 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2ATMALDH1A1MAPTHPGD | |
| SCHEMBL12103681 | 0.73 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1MAPTNPSR1CYP2C9 | |
| SCHEMBL8971203 | 0.73 | RXRA (0.45) | SMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL8971980 | 0.73 | SMN1; SMN2 (0.42) | SMN1; SMN2ATMALDH1A1MAPTHPGD | |
| SCHEMBL15893569 | 0.73 | CYP2D6 (0.36) | SMN1; SMN2ATMALDH1A1MAPTHPGD | |
| SCHEMBL18877756 | 0.72 | CYP2D6 (0.41) | SMN1; SMN2ATMALDH1A1MAPTHPGD | |
| SCHEMBL8971390 | 0.71 | SMN1; SMN2 (0.49) | SMN1; SMN2ATMALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100248365-A1 | GANGLIOSIDE BIOSYNTHESIS MODULATORS | ZACHARON PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | US | disclosed |
| US-20100248365-A1 | GANGLIOSIDE BIOSYNTHESIS MODULATORS | ZACHARON PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100248365-A1 | GANGLIOSIDE BIOSYNTHESIS MODULATORS | UGCG, MAGT1, STT3B | SMN1; SMN2 3220/4885ATM 3727/4885ALDH1A1 2578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.