SCHEMBL28148332

SCHEMBL28148332

CC(=O)O[C@]1(C(C)=O)[C@H](O)[C@@H](CO)O[C@@]1(C(C)=O)n1cc(C)c(=O)[nH]c1=O

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TK1 P04183 4/20 0.37
ALDH1A1 P00352 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
TYMP P19971 1/20 0.37
TK2 O00142 2/20 0.36
LMNA P02545 1/20 0.36
ALB P02768 1/20 0.36
POLB P06746 1/20 0.36
ADRA1A P35348 1/20 0.36
BLM P54132 1/20 0.36
RNASE1 P07998 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29134987 0.89 TK2 (0.35) TK1TK2
SCHEMBL28289547 0.84 TK2 (0.46) TK1NPSR1TK2BLM
SCHEMBL4653180 0.83 TK1 (0.40) TK1ALDH1A1NPSR1TYMPTK2
SCHEMBL60518 0.82 SLC28A1 (0.39) ALDH1A1LMNA
SCHEMBL4662920 0.82 TK1 (0.39) TK1ALDH1A1NPSR1TYMPTK2
SCHEMBL9237885 0.75 LMNA (0.37) LMNA
SCHEMBL28189821 0.73 TK1 (0.41) TK1ALDH1A1NPSR1TYMPTK2
SCHEMBL1120571 0.73 HINT1 (0.42) TK1ALDH1A1LMNABLM
SCHEMBL766624 0.72 PYGM (0.42) TK1NPSR1TK2LMNAADRA1A
SCHEMBL381848 0.72 PDE3A (0.41) ALDH1A1LMNAALBPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106632554-B The method that 2 ', 3 '-two -3 '-deoxythymidine of dehydrogenation are synthesized by triacetyl 5-methyl-uridin 洛阳师范学院 2019-10-08 CN claimed
CN-106632554-A Method for synthesizing 2',3'-dehydrogenation-3'-deoxythymidine by using triacetyl 5-methyluridine 洛阳师范学院 2017-05-10 CN claimed
CN-106632554-B The method that 2 ', 3 '-two -3 '-deoxythymidine of dehydrogenation are synthesized by triacetyl 5-methyl-uridin 洛阳师范学院 2019-10-08 CN disclosed
CN-106632554-B The method that 2 ', 3 '-two -3 '-deoxythymidine of dehydrogenation are synthesized by triacetyl 5-methyl-uridin 洛阳师范学院 2019-10-08 CN disclosed
CN-106632554-B The method that 2 ', 3 '-two -3 '-deoxythymidine of dehydrogenation are synthesized by triacetyl 5-methyl-uridin 洛阳师范学院 2019-10-08 CN disclosed
CN-106632554-A Method for synthesizing 2',3'-dehydrogenation-3'-deoxythymidine by using triacetyl 5-methyluridine 洛阳师范学院 2017-05-10 CN disclosed
CN-106632554-A Method for synthesizing 2',3'-dehydrogenation-3'-deoxythymidine by using triacetyl 5-methyluridine 洛阳师范学院 2017-05-10 CN disclosed
CN-106632554-A Method for synthesizing 2',3'-dehydrogenation-3'-deoxythymidine by using triacetyl 5-methyluridine 洛阳师范学院 2017-05-10 CN disclosed