SCHEMBL1120571

SCHEMBL1120571

CC(=O)O[C@]1(C(C)=O)[C@H](O)[C@@H](CO)O[C@@]1(C(C)=O)n1cnc2c(=O)[nH]c(N)nc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HINT1 P49773 3/20 0.42
BLM P54132 2/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
CYP3A4 P08684 1/20 0.41
NFKB1 P19838 1/20 0.41
VCP P55072 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HIF1A Q16665 1/20 0.41
HPGD P15428 1/20 0.41
PNP P00491 2/20 0.40
USP2 O75604 1/20 0.40
TSHR P16473 1/20 0.40
EDNRA P25101 1/20 0.40
HTR2A P28223 1/20 0.40
RECQL P46063 1/20 0.40
HBB P68871 1/20 0.40
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27975681 0.81 PNP (0.42) HINT1BLMMEN1ALDH1A1LMNA
SCHEMBL12813023 0.80 DNMT1 (0.41) BLMALDH1A1LMNANFKB1HBB
SCHEMBL5935890 0.79 MEN1 (0.40) HINT1BLMMEN1ALDH1A1LMNA
SCHEMBL10868773 0.79 PI4KA (0.33) MEN1KMT2ASMN1; SMN2HIF1AADORA3
SCHEMBL4754458 0.78 HINT1 (0.44) HINT1BLMMEN1ALDH1A1LMNA
SCHEMBL28252469 0.78 TK1 (0.41) HINT1BLMMEN1ALDH1A1LMNA
SCHEMBL443377 0.78 ADORA3 (0.45) HINT1BLMMEN1ALDH1A1LMNA
SCHEMBL381848 0.76 PDE3A (0.41) ALDH1A1LMNASMN1; SMN2PDE3A
SCHEMBL1964956 0.76 TK1 (0.46) HINT1BLMMEN1ALDH1A1LMNA
SCHEMBL237755 0.76 HPGD (0.46) HINT1BLMMEN1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102485738-A Synthetic method of LIANYUNGANG SHENGHE BIOTECHNOLOGY CO LTD 2012-06-06 CN claimed
EP-0827960-A1 Process for producing purine derivatives Ajinomoto Co., Inc. (JP) 1998-03-11 EP claimed
JP-10087664-A None JP disclosed
US-20250171482-A1 DEACYLATION OF CARBOHYDRATE COMPOUNDS UNIVERSITY OF SOUTH ALABAMA 2025-05-29 US disclosed
CN-118632856-A By bringing the carbohydrate deacylation of the substance 益力舒健康公司 2024-09-10 CN disclosed
WO-2023178017-A1 DEACYLATION OF CARBOHYDRATE COMPOUNDS ELYSIUM HEALTH INC. (US) 2023-09-21 WO disclosed
US-20180066009-A1 Nucleosides and Oligonucleotides for Studies on Reversal of Cytotoxic and Mutagenic Damage of DNA and as Diagnostics Tools CHEMGENES CORP (US) 2018-03-08 US disclosed
US-9718855-B2 Nucleosides and oligonucleotides for studies on reversal of cytotoxic and mutagenic damage of DNA and as diagnostics tools CHEMGENES CORPORATION (US) 2017-08-01 US disclosed
US-20140350234-A1 Nucleosides and Oligonucleotides for Studies on Reversal of Cytotoxic and Mutagenic Damage of DNA and as Diagnostics Tools CHEMGENES CORPORATION (US) 2014-11-27 US disclosed
US-8785619-B1 Nucleosides and oligonucleotides for studies on reversal of cytotoxic and mutagenic damage of DNA potential diagnostics tools CHEMGENES CORPORATION (US) 2014-07-22 US disclosed
CN-101830955-B Synthesizing process of antineoplastic agent clofarabine ZHEJIANG HISUN PHARM CO LTD 2013-09-11 CN disclosed
JP-H1087664-A PRODUCTION OF PURINE DERIVATIVE AJINOMOTO CO INC 1998-04-07 JP disclosed
EP-0827960-A1 Process for producing purine derivatives Ajinomoto Co., Inc. (JP) 1998-03-11 EP disclosed
EP-0771204-A1 METHODS FOR TREATING SEPSIS OR INFLAMMATORY DISEASES WITH OXYPURINE NUCLEOSIDES PRO-NEURON, INC. (US) 1997-05-07 EP disclosed
WO-1996004923-A1 METHODS FOR TREATING SEPSIS OR INFLAMMATORY DISEASES WITH OXYPURINE NUCLEOSIDES PRO-NEURON, INC. (US) 1996-02-22 WO disclosed
EP-0570519-A4 OXYPURINE NUCLEOSIDES AND THEIR CONGENERS, AND ACYL DERIVATIVES THEREOF, FOR IMPROVEMENT OF HEMATOPOIESIS PRO NEURON INC (US) 1996-02-21 EP disclosed
EP-0570519-A1 OXYPURINE NUCLEOSIDES AND THEIR CONGENERS, AND ACYL DERIVATIVES THEREOF, FOR IMPROVEMENT OF HEMATOPOIESIS PRO-NEURON, INC. (US) 1993-11-24 EP disclosed
WO-1992013561-A1 OXYPURINE NUCLEOSIDES AND THEIR CONGENERS, AND ACYL DERIVATIVES THEREOF, FOR IMPROVEMENT OF HEMATOPOIESIS PRO-NEURON, INC. (US) 1992-08-20 WO disclosed
EP-0269574-A2 Novel adenosine derivatives and pharmaceutical compositions containing them as an active ingredient NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) 1988-06-01 EP disclosed
EP-0191624-A2 Gold-purine antitumor agents ENGELHARD CORPORATION (US) 1986-08-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250171482-A1 DEACYLATION OF CARBOHYDRATE COMPOUNDS FUT5, DDOST, TREH HINT1 1418/4885BLM 3678/4885MEN1 1854/4885
US-20140350234-A1 Nucleosides and Oligonucleotides for Studies on Reversal of Cytotoxic and Mutagenic Damage of DNA and as Diagnostics Tools UNG, OGG1, ADAR HINT1 295/4885BLM 124/4885MEN1 2445/4885
US-20180066009-A1 Nucleosides and Oligonucleotides for Studies on Reversal of Cytotoxic and Mutagenic Damage of DNA and as Diagnostics Tools UNG, OGG1, ADAR HINT1 295/4885BLM 124/4885MEN1 2445/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.