Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.41 |
| ▸ | MMP9 | P14780 | 3/20 | 0.41 |
| ▸ | MMP12 | P39900 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | MMP14 | P50281 | 2/20 | 0.40 |
| ▸ | MMP16 | P51512 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KYNU | Q16719 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15302641 | 0.87 | MMP2 (0.41) | MMP2MMP9MMP12ALDH1A1MMP8 | |
| SCHEMBL4478031 | 0.78 | MEN1 (0.38) | MMP2MMP9MMP12ALDH1A1MMP8 | |
| SCHEMBL2208256 | 0.77 | MMP2 (0.62) | MMP2MMP9MMP12ALDH1A1ITGAV | |
| SCHEMBL27991976 | 0.77 | LMNA (0.44) | MMP2MMP9MMP12ALDH1A1ITGAV | |
| SCHEMBL1822253 | 0.76 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10AKR1C3AKR1C2 | |
| SCHEMBL1928791 | 0.75 | ACP3 (0.43) | ALDH1A1CYP3A4LMNAHSD17B10CYP1A2 | |
| SCHEMBL10580121 | 0.75 | LMNA (0.41) | ALDH1A1LMNAHSD17B10CYP1A2TSHR | |
| SCHEMBL4062734 | 0.75 | LMNA (0.41) | ALDH1A1LMNAHSD17B10CYP1A2TSHR | |
| SCHEMBL10180789 | 0.75 | TSHR (0.52) | ALDH1A1ITGAVBCAT2CYP3A4CYP2D6 | |
| SCHEMBL6773227 | 0.75 | TSHR (0.57) | ALDH1A1LMNAHSD17B10CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106795158-A | Tetrahydropyrazolopyridine derivatives as ghrelin receptor agonists | 拉夸里亚创药株式会社 | 2017-05-31 | — | — | CN | disclosed |