SCHEMBL28150786

SCHEMBL28150786

Cc1cc([SH]2CCCCC2)ccc1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 13/20 0.44
ESR2 Q92731 11/20 0.44
TP53 P04637 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
PDE10A Q9Y233 1/20 0.41
AR P10275 3/20 0.37
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
G6PD P11413 1/20 0.35
CYP2C9 P11712 1/20 0.35
PKM P14618 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
MAPK1 P28482 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27893504 0.78 ACHE (0.44) ESR1ESR2KDM4EALDH1A1CYP1A2
SCHEMBL29039139 0.75 CA1 (0.44) ESR1ESR2KDM4EALDH1A1CYP1A2
SCHEMBL25865365 0.74 HTT (0.30)
SCHEMBL26156858 0.71 POLB (0.30)
SCHEMBL25477065 0.70 ACHE (0.40) TDP1ALDH1A1
SCHEMBL27524308 0.70 ALDH1A1 (0.40) ESR1ESR2KDM4EALDH1A1CYP1A2
SCHEMBL26477041 0.68 CA3 (0.42) ESR1ESR2KDM4EALDH1A1CYP1A2
SCHEMBL25658016 0.67 ALDH1A1 (0.33) ALDH1A1PKM
SCHEMBL2000010 0.63
SCHEMBL29429121 0.62 HSD17B1 (0.68) ESR1ESR2TP53TDP1PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106715615-A Ultraviolet curable transfer coating for applying nanometer sized metal particles to polymer surface 沙特基础工业全球技术有限公司 2017-05-24 CN disclosed