SCHEMBL2815459

SCHEMBL2815459

CC(N)C(=O)NC(CCCNC(=N)N)C(=O)NC(Cc1ccccc1)C(=O)O.[Cu]

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 15/20 0.55
NPY1R P25929 9/20 0.55
NPY5R Q15761 8/20 0.55
NPY2R P49146 5/20 0.55
GNPAT O15228 1/20 0.50
KISS1R Q969F8 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31184376 0.99 NPY4R (0.55) NPY4RNPY1RNPY5RNPY2RGNPAT
SCHEMBL5598820 0.99 NPY4R (0.55) NPY4RNPY1RNPY5RNPY2RGNPAT
SCHEMBL5598812 0.99 NPY4R (0.55) NPY4RNPY1RNPY5RNPY2RGNPAT
SCHEMBL31184322 0.99 NPY4R (0.55) NPY4RNPY1RNPY5RNPY2RGNPAT
SCHEMBL4589880 0.98 NPY4R (0.55) NPY4RNPY1RNPY5RNPY2RGNPAT
SCHEMBL31420009 0.95 GNPAT (0.56) NPY4RNPY1RNPY5RNPY2RGNPAT
SCHEMBL30866924 0.94 NPY4R (0.56) NPY4RNPY1RNPY5RNPY2RGNPAT
SCHEMBL30264923 0.92 NPY4R (0.54) NPY4RNPY1RNPY5RNPY2RGNPAT
SCHEMBL30265523 0.92 NPY4R (0.54) NPY4RNPY1RNPY5RNPY2RGNPAT
SCHEMBL24059390 0.92 NPY4R (0.55) NPY4RNPY1RNPY5RNPY2RGNPAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100249042-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF EYELASHES AND EYEBROWS PROCYTE CORPORATION (US) 2010-09-30 US disclosed
EP-1613302-B1 PRESERVED AND STABLE COMPOSITIONS CONTAINING PEPTIDE COPPER COMPLEXES AND METHODS RELATED THERETO PROCYTE CORP (US) 2009-12-23 EP disclosed
US-7179789-B2 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2007-02-20 US disclosed
US-7128923-B2 Preserved and stable compositions containing peptide copper complexes and method related thereto PROCYTE CORPORATION (US) 2006-10-31 US disclosed
US-20060052287-A1 Polyethylene glycol - peptide copper complexes and compositions and methods related thereto PROCYTE CORPORATION (US) 2006-03-09 US disclosed
US-20050209130-A1 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2005-09-22 US disclosed
US-20050197282-A1 for topical administration of peptide copper complex with corticosteroids, coal tar, anthralin, calcipotriene, and tazarotene; dermatology; cosmetics PROCYTE CORPORATION (US) 2005-09-08 US disclosed
US-6927206-B2 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2005-08-09 US disclosed
US-6927205-B2 Compositions and methods for treatment of psoriasis PROCYTE CORPORATION (US) 2005-08-09 US disclosed
EP-0765152-B1 STIMULATION OF HAIR GROWTH BY PEPTIDE-COPPER COMPLEXES PROCYTE CORP (US) 2001-11-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050209130-A1 Compositions and methods for treatment of rosacea CUTA, AOC1, RCN1 NPY4R 811/4885NPY1R 171/4885NPY5R 380/4885
US-20060052287-A1 Polyethylene glycol - peptide copper complexes and compositions and methods related thereto NGLY1, CUTA, TFRC NPY4R 1065/4885NPY1R 269/4885NPY5R 596/4885
US-20100249042-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF EYELASHES AND EYEBROWS CUTA, TYR, EYA3 NPY4R 785/4885NPY1R 300/4885NPY5R 402/4885
US-20050197282-A1 for topical administration of peptide copper complex with corticosteroids, coal tar, anthralin, calcipotriene, and tazarotene; dermatology; cosmetics PTH1R, TSLP, CYP27B1 NPY4R 797/4885NPY1R 936/4885NPY5R 1358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.