Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28156085 | 0.81 | MAPT (0.45) | MAPTTSHRL3MBTL1TP53GAA | |
| SCHEMBL28846115 | 0.75 | MTNR1A (0.56) | TSHRSMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL28156812 | 0.75 | LDHA (0.48) | MAPTTSHRL3MBTL1THRBMTNR1A | |
| SCHEMBL28156097 | 0.72 | PTGS2 (0.47) | L3MBTL1SMN1; SMN2GAANPSR1MTNR1A | |
| SCHEMBL28156828 | 0.71 | GPR35 (0.43) | MAPTL3MBTL1TP53SMN1; SMN2THRB | |
| SCHEMBL28156107 | 0.70 | L3MBTL1 (0.44) | L3MBTL1GAAMTNR1AMTNR1B | |
| SCHEMBL6703975 | 0.68 | ALDH1A1 (0.42) | MAPTSMN1; SMN2GAANPSR1 | |
| SCHEMBL7681737 | 0.67 | KDM4E (0.42) | MAPTTSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL26581456 | 0.65 | ALDH1A1 (0.40) | — | |
| SCHEMBL26036872 | 0.62 | MCL1 (0.37) | GAATHRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106831533-A | A kind of synthetic method of tryptophol and tryptamines analog derivative | 北京大学 | 2017-06-13 | — | — | CN | disclosed |