Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 7/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28158363 | 0.86 | LIPE (0.39) | KCNH2OPRL1 | |
| SCHEMBL28158979 | 0.81 | CHRM5 (0.38) | OPRL1KIF11 | |
| SCHEMBL28158980 | 0.79 | FAAH (0.40) | DRD2DRD3OPRL1NOTUM | |
| SCHEMBL28158397 | 0.77 | KCNH2 (0.43) | KCNH2DRD2DRD3DHFROPRL1 | |
| SCHEMBL28158973 | 0.77 | HCAR1 (0.39) | KCNH2DRD2EPHX2 | |
| SCHEMBL30292820 | 0.76 | SIGMAR1 (0.38) | — | |
| SCHEMBL21815682 | 0.76 | SIGMAR1 (0.38) | — | |
| SCHEMBL5801010 | 0.76 | ALDH1A1 (0.42) | DHFR | |
| SCHEMBL28158376 | 0.75 | DHFR (0.43) | KCNH2DRD2DRD3DHFROPRL1 | |
| SCHEMBL1408252 | 0.74 | SIGMAR1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105530938-B | Compounds for the treatment of diseases caused by retroviruses | ABIVAX公司 | 2019-10-22 | — | — | CN | claimed |
| CN-106928194-B | Compounds for the treatment of premature aging and especially premature aging | ABIVAX公司 | 2019-11-12 | — | — | CN | disclosed |
| CN-105530938-B | Compounds for the treatment of diseases caused by retroviruses | ABIVAX公司 | 2019-10-22 | — | — | CN | disclosed |
| CN-106905232-B | Compounds for the treatment of premature aging and especially premature aging | ABIVAX公司 | 2019-09-27 | — | — | CN | disclosed |
| CN-106928205-B | Compounds for the treatment of premature aging and especially premature aging | ABIVAX公司 | 2019-09-24 | — | — | CN | disclosed |
| CN-109776496-A | Compounds for the treatment of premature aging and especially premature aging | ABIVAX公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-104844510-B | Compounds for the treatment of premature aging and especially premature aging | ABIVAX公司 | 2019-04-23 | — | — | CN | disclosed |
| CN-104945379-B | Compounds for the treatment of premature aging and especially premature aging | ABIVAX公司 | 2018-11-30 | — | — | CN | disclosed |
| CN-104945378-B | Compounds for the treatment of premature aging and especially premature aging | ABIVAX公司 | 2018-11-20 | — | — | CN | disclosed |
| CN-104844570-B | Compounds for the treatment of premature aging and especially premature aging | ABIVAX公司 | 2018-11-02 | — | — | CN | disclosed |
| CN-106928205-A | Compounds for the treatment of premature aging and especially premature aging | ABIVAX公司 | 2017-07-07 | — | — | CN | disclosed |
| CN-106928194-A | Compounds for the treatment of premature aging and especially premature aging | ABIVAX公司 | 2017-07-07 | — | — | CN | disclosed |
| CN-106905232-A | Compounds for the treatment of premature aging and especially premature aging | ABIVAX公司 | 2017-06-30 | — | — | CN | disclosed |