Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18856847 | 0.77 | ADRA2A (0.44) | MAPTRAB9ANPC1RECQLMEN1 | |
| SCHEMBL2297554 | 0.77 | LMNA (0.50) | MAPTRAB9ANPC1GAAL3MBTL1 | |
| SCHEMBL11812041 | 0.77 | MAPT (0.81) | MAPTRAB9ANPC1GAAL3MBTL1 | |
| SCHEMBL1121223 | 0.76 | RAB9A (0.67) | MAPTRAB9ANPC1GAAL3MBTL1 | |
| SCHEMBL8443603 | 0.74 | SYK (0.48) | KDM4EMEN1KMT2AAURKASYK | |
| SCHEMBL1459772 | 0.73 | MAPT (1.00) | MAPTRAB9ANPC1GAAL3MBTL1 | |
| SCHEMBL39057 | 0.73 | MAPT (1.00) | MAPTRAB9ANPC1GAAL3MBTL1 | |
| SCHEMBL11461135 | 0.71 | HDAC3 (0.63) | MAPTRAB9ANPC1GAAL3MBTL1 | |
| SCHEMBL22191045 | 0.71 | HDAC3 (0.59) | MAPTRAB9ANPC1GAAL3MBTL1 | |
| SCHEMBL2495024 | 0.71 | NR4A1 (0.61) | MAPTRAB9ANPC1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104428289-B | As the triazole compounds of antivirotic | 弗·哈夫曼-拉罗切有限公司 | 2017-06-23 | — | — | CN | claimed |