Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | AURKA | O14965 | 2/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.44 |
| ▸ | CDK1 | P06493 | 2/20 | 0.44 |
| ▸ | LYN | P07948 | 2/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.44 |
| ▸ | MARK3 | P27448 | 2/20 | 0.44 |
| ▸ | BLK | P51451 | 2/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.44 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.44 |
| ▸ | MARK2 | Q7KZI7 | 2/20 | 0.44 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1923749 | 0.83 | KCNH3 (0.59) | KCNH3 | |
| SCHEMBL18856712 | 0.78 | KDR (0.49) | CDK2AURKACDK1KDRAURKB | |
| SCHEMBL18856786 | 0.78 | ALDH1A1 (0.50) | MAPTMAPK1NPC1RAB9AHSD17B10 | |
| SCHEMBL4672987 | 0.78 | NFKB1 (0.53) | LMNAGFERCDK2MAPTMAPK1 | |
| SCHEMBL28164686 | 0.77 | MAPT (0.55) | LMNAGAAMAPTMAPK1AURKA | |
| SCHEMBL18856847 | 0.76 | ADRA2A (0.44) | CDK2MAPTCDK1NPC1RAB9A | |
| SCHEMBL8443603 | 0.76 | SYK (0.48) | AURKACDK1IKBKBMEN1KMT2A | |
| SCHEMBL18754966 | 0.75 | SYK (0.45) | MAPK1MEN1KMT2ATSHRSYK | |
| SCHEMBL18856454 | 0.75 | EGFR (0.42) | KCNH3JAK2NTRK1SYK | |
| SCHEMBL18856705 | 0.75 | GRM4 (0.50) | LMNAMAPTMAPK1AURKAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4722199-A1 | AZOLE COMPOUND, METHOD FOR SYNTHESIZING SAID AZOLE COMPOUND, AND USE THEREOF | SHIKOKU CHEMICALS CORPORATION (JP) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024247919-A1 | AZOLE COMPOUND, METHOD FOR SYNTHESIZING SAID AZOLE COMPOUND, AND USE THEREOF | 四国化成工業株式会社 | 2024-12-05 | — | — | WO | disclosed |
| CN-116675677-B | C8 urushiol derivative and preparation method and application thereof | 中国林业科学研究院林产化学工业研究所 | 2023-09-26 | — | — | CN | disclosed |
| CN-116406231-A | Molecules having certain pesticidal utility, and intermediates, compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2023-07-07 | — | — | CN | disclosed |
| US-20160002180-A1 | ANTIVIRAL COMPOUNDS | HOFFMANN LA ROCHE (US) | 2016-01-07 | — | — | US | disclosed |
| US-20130310433-A1 | THIOPHENE-CARBOXAMIDES USEFUL AS INHIBITORS OF PROTEIN KINASES | VERTEX PHARMACEUTICALS INCORPORATED | 2013-11-21 | — | — | US | disclosed |
| US-20130310433-A1 | THIOPHENE-CARBOXAMIDES USEFUL AS INHIBITORS OF PROTEIN KINASES | VERTEX PHARMACEUTICALS INCORPORATED | 2013-11-21 | — | — | US | disclosed |
| US-8481578-B2 | Thiophene-carboxamides useful as inhibitors of protein kinases | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-07-09 | — | — | US | disclosed |
| US-8481578-B2 | Thiophene-carboxamides useful as inhibitors of protein kinases | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-07-09 | — | — | US | disclosed |
| EP-2019826-B1 | THIOPHENE-CARBOXAMIDES USEFUL AS INHIBITORS OF PROTEIN KINASES | VERTEX PHARMA (US) | 2012-08-29 | — | — | EP | disclosed |
| US-20080070965-A1 | Thiophene-carboxamides useful as inhibitors of protein kinases | VERTEX PHARMACEUTICALS INCORPORATED | 2008-03-20 | — | — | US | disclosed |
| WO-2007139795-A1 | THIOPHENE-CARBOXAMIDES USEFUL AS INHIBITORS OF PROTEIN KINASES | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2007-12-06 | — | — | WO | disclosed |
| WO-2007139795-A1 | THIOPHENE-CARBOXAMIDES USEFUL AS INHIBITORS OF PROTEIN KINASES | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2007-12-06 | — | — | WO | disclosed |
| US-7226920-B2 | Aminotriazole compounds useful as inhibitors of protein kinases | VERTEX PHARMACEUTICALS INC. (US) | 2007-06-05 | — | — | US | disclosed |
| US-7226920-B2 | Aminotriazole compounds useful as inhibitors of protein kinases | VERTEX PHARMACEUTICALS INC. (US) | 2007-06-05 | — | — | US | disclosed |
| US-7226920-B2 | Aminotriazole compounds useful as inhibitors of protein kinases | VERTEX PHARMACEUTICALS INC. (US) | 2007-06-05 | — | — | US | disclosed |
| EP-1663211-A1 | AMINOTRIAZOLE COMPOUNDS USEFUL AS INHIBITORS OF PROTEIN KINASES | Vertex Pharmaceuticals Incorporated (US) | 2006-06-07 | — | — | EP | disclosed |
| US-20050261268-A1 | Aminotriazole compounds useful as inhibitors of protein kinases | VERTEX PHARMACEUTICALS INCORPORATED | 2005-11-24 | — | — | US | disclosed |
| WO-2005013982-A1 | AMINOTRIAZOLE COMPOUNDS USEFUL AS INHIBITORS OF PROTEIN KINASES | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2005-02-17 | — | — | WO | disclosed |
| US-4182630-A | COLOR PHOTOGRAPHY | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1980-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130310433-A1 | THIOPHENE-CARBOXAMIDES USEFUL AS INHIBITORS OF PROTEIN KINASES | MAP3K20, MAP3K5, PACSIN2 | LMNA 3756/4885GAA 1186/4885GFER 3408/4885 |
| US-20080070965-A1 | Thiophene-carboxamides useful as inhibitors of protein kinases | MAP3K20, MAP3K5, PACSIN2 | LMNA 3756/4885GAA 1186/4885GFER 3408/4885 |
| US-20160002180-A1 | ANTIVIRAL COMPOUNDS | HAVCR2, EIF2AK2, MAVS | LMNA 3602/4885GAA 58/4885GFER 3650/4885 |
| US-20050261268-A1 | Aminotriazole compounds useful as inhibitors of protein kinases | MAP3K20, MAP3K5, MAP3K1 | LMNA 3410/4885GAA 2168/4885GFER 2984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.