Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 2/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.41 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.41 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18723995 | 0.77 | TYMS (0.38) | KCNH2DHODHMEN1KMT2AABCG2 | |
| SCHEMBL2297554 | 0.76 | LMNA (0.50) | SYKMEN1KMT2AIGF1RCDK1 | |
| SCHEMBL18723854 | 0.76 | TNIK (0.37) | KCNH2ABCG2IKBKB | |
| SCHEMBL21914834 | 0.75 | CTSK (0.58) | SYKKCNH2SCN5ASCN9ADHODH | |
| SCHEMBL1741981 | 0.74 | KCNH2 (0.55) | SYKKCNH2SCN5ASCN9AMEN1 | |
| SCHEMBL1881253 | 0.73 | CDC7 (0.61) | SYKKCNH2SCN5ASCN9AMEN1 | |
| SCHEMBL28610259 | 0.73 | SYK (0.51) | SYKKCNH2SCN5ASCN9ADHODH | |
| SCHEMBL18856847 | 0.72 | ADRA2A (0.44) | SYKMEN1KMT2ACDK1GSK3B | |
| SCHEMBL395539 | 0.72 | CA2 (0.52) | SYKDHODHMEN1KMT2AABCG2 | |
| SCHEMBL21915358 | 0.71 | CTSK (0.54) | SYKKCNH2SCN5ASCN9ADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641785-B1 | TRIAZOLYLATED TERTIARY AMINE COMPOUND OR SALT THEREOF | YAMANOUCHI PHARMA CO LTD (JP) | 1999-10-27 | — | — | EP | disclosed |