Water

Water

SCHEMBL28170254

CC1CCCC[Si]1(C)C.O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27315228 0.97
SCHEMBL19428195 0.97
Methane SCHEMBL27284485 0.94
Fluoride SCHEMBL27553092 0.94
Iodide SCHEMBL27291274 0.94
Bromide SCHEMBL27681667 0.94
Ethane SCHEMBL28062117 0.94
Ammonia Solution, Strong SCHEMBL27756602 0.94
SCHEMBL7434852 0.94 TSHR (0.32)
SCHEMBL27595178 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110522688-A A kind of preparation and its application of alkannin powder SHANGHAI INST TECH 2019-12-03 CN claimed
CN-110320676-A Contact lens products 星欧光学股份有限公司 2019-10-11 CN claimed
CN-110141534-A A kind of moisturizing metal eye shadow and its manufacturing method 中山市美源化妆品有限公司 2019-08-20 CN claimed
CN-110092985-A A kind of sound insulation thermal-ageing-resistant rubber pad 陈令 2019-08-06 CN claimed
CN-110055041-A A kind of Anti-pressure Foamed water shutoff agent 南京思宇环保科技有限公司 2019-07-26 CN claimed
CN-110037929-A A kind of moisturizing maintenance essence stick and preparation method thereof 刘桂琴 2019-07-23 CN claimed
CN-109966184-A A kind of suspension oil droplet makeup remover and preparation method thereof 广州玮弘祺生物科技有限公司 2019-07-05 CN claimed
CN-109939017-A One kind pure oil lipstick product having repairing effect and preparation method thereof 广东三好科技有限公司 2019-06-28 CN claimed
CN-109875957-A A kind of skin wound nursing ointment and preparation method thereof 重庆美迪森医药科技有限公司 2019-06-14 CN claimed
CN-109810798-A Main lotion of cold washing for textile and preparation method thereof 北京日光旭升精细化工技术研究所 2019-05-28 CN claimed
CN-109810796-A A kind of color protection exempts from brush liquid detergent and preparation method thereof 北京日光旭升精细化工技术研究所 2019-05-28 CN claimed
CN-109776595-A The technique for purifying bis- (trimethylsiloxy group) methyl of (3- methacryloxy -2- hydroxy propyloxy group) propyl 爱生华(苏州)光学有限公司 2019-05-21 CN claimed
CN-109568215-A A kind of moist moisturizing maintenance essence cream and preparation method thereof containing dissolubility beeswax 浙江维珍生物科技有限公司 2019-04-05 CN claimed
CN-109568158-A A kind of compact eye cream immediately 广州尚姿化妆品有限公司 2019-04-05 CN claimed
CN-109431822-A A kind of foundation emulsion and preparation method thereof of essential oil and powder separation 广州娇彩化妆品有限公司 2019-03-08 CN claimed
CN-109394590-A A kind of soft foundation compositions of crease-resistant silk and preparation method thereof 广州艾蓓生物科技有限公司 2019-03-01 CN claimed
CN-109316382-A A kind of elasticity color make-up product and preparation method thereof 花安堂生物科技集团有限公司 2019-02-12 CN claimed
CN-108904333-A A kind of liquid blush and preparation method thereof 广州铭泽恒基生物科技有限公司 2018-11-30 CN claimed
CN-105189419-B Metathesis process including being extracted the ethene of formation by means of film 阿肯马法国公司 2018-01-19 CN claimed
CN-107312496-A A kind of cementability add-on type liquid silicon rubber 杭州师范大学 2017-11-03 CN claimed