Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28175124 | 0.74 | POLB (0.45) | CA12CA1CA2CA9POLB | |
| SCHEMBL288348 | 0.67 | CA2 (0.39) | CA12CA1CA2CA9 | |
| SCHEMBL28776625 | 0.66 | KMT2A (0.33) | POLB | |
| SCHEMBL1955893 | 0.63 | CA1 (0.42) | CA12CA1CA2CA9POLB | |
| SCHEMBL31605937 | 0.63 | NUDT1 (0.33) | — | |
| SCHEMBL27262616 | 0.61 | — | — | |
| SCHEMBL28193727 | 0.61 | PDPK1 (0.34) | — | |
| SCHEMBL8148844 | 0.60 | RECQL (0.46) | CA12CA1CA2CA9POLB | |
| SCHEMBL15041407 | 0.58 | RECQL (0.45) | CA12CA1CA2CA9POLB | |
| SCHEMBL27703414 | 0.58 | CA12 (0.31) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102762575-B | polycyclic compounds and methods of use thereof | SUNOVION PHARMACEUTICALS INC | 2015-04-15 | — | — | CN | disclosed |
| CN-104507928-A | Heterocyclic modulators of lipid synthesis | 3 V BIOSCIENCES INC | 2015-04-08 | — | — | CN | disclosed |
| CN-104193761-A | MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC | 2014-12-10 | — | — | CN | disclosed |
| CN-102762575-A | Polycyclic compounds and methods of use thereof | SUNOVION PHARMACEUTICALS INC | 2012-10-31 | — | — | CN | disclosed |