Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PLEC | Q15149 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27586113 | 0.83 | GABRA1 (0.39) | MAPTKDM4EALDH1A1GRIN1GRIN2B | |
| SCHEMBL27759078 | 0.81 | GRIN2B (0.42) | L3MBTL1ALDH1A1GRIN1GRIN2BGAA | |
| SCHEMBL28272597 | 0.78 | NR3C2 (0.43) | KDM4EALDH1A1LMNAGAAKMT2A | |
| SCHEMBL27500366 | 0.78 | FDPS (0.46) | MAPTKDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL27837868 | 0.78 | SMN1; SMN2 (0.39) | MAPTNPSR1KDM4EALDH1A1LMNA | |
| SCHEMBL27737954 | 0.78 | CYP4F2 (0.41) | L3MBTL1MAPTNPSR1ALDH1A1LMNA | |
| SCHEMBL27758897 | 0.77 | CTSK (0.35) | MAPTNPSR1ALDH1A1LMNAKMT2A | |
| SCHEMBL27668919 | 0.77 | ALDH1A1 (0.47) | KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL27852818 | 0.77 | RIPK1 (0.43) | MAPTKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL27839098 | 0.77 | CTSK (0.35) | MAPTALDH1A1LMNAKMT2AHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107400092-A | Pyridine derivatives and preparation method thereof and its purposes in medicine | 浙江海正药业股份有限公司 | 2017-11-28 | — | — | CN | disclosed |