Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28185115 | 0.84 | P2RX7 (0.38) | ALDH1A1POLBP2RX7 | |
| SCHEMBL28418049 | 0.68 | TRPM8 (0.32) | ALDH1A1 | |
| SCHEMBL27788485 | 0.66 | POLB (0.39) | POLB | |
| SCHEMBL6592179 | 0.66 | POLB (0.47) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL27862268 | 0.66 | POLB (0.39) | POLB | |
| SCHEMBL27529146 | 0.63 | POLB (0.44) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL27266272 | 0.63 | ALDH1A1 (0.40) | ALDH1A1POLBSMN1; SMN2HPGD | |
| SCHEMBL27322913 | 0.63 | POLB (0.41) | POLBSMN1; SMN2 | |
| SCHEMBL28687108 | 0.62 | POLB (0.40) | POLBSMN1; SMN2 | |
| SCHEMBL9435372 | 0.61 | ALDH1A1 (0.38) | ALDH1A1POLBSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107417767-A | Dipeptide compound, its preparation method and the application of piperidines or piperazine structure | 杭州市西溪医院 | 2017-12-01 | — | — | CN | disclosed |