Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 2/20 | 0.30 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28185741 | 0.84 | ALDH1A1 (0.36) | P2RX7POLBALDH1A1 | |
| SCHEMBL25753684 | 0.68 | POLB (0.46) | MKNK1MKNK2POLBKDM4E | |
| SCHEMBL27735180 | 0.66 | SIGMAR1 (0.41) | POLBALDH1A1 | |
| Formic Acid SCHEMBL6282993 | 0.66 | PLD1 (0.47) | ALDH1A1KDM4EPLD1 | |
| SCHEMBL3334612 | 0.65 | P2RX7 (0.30) | P2RX7 | |
| SCHEMBL27788485 | 0.64 | POLB (0.39) | POLBKDM4E | |
| SCHEMBL6592179 | 0.64 | POLB (0.47) | POLBALDH1A1KDM4E | |
| SCHEMBL27862268 | 0.64 | POLB (0.39) | POLBKDM4E | |
| SCHEMBL11076260 | 0.64 | MKNK1 (0.41) | MKNK1MKNK2POLBALDH1A1 | |
| SCHEMBL4820083 | 0.64 | CYP3A4 (0.55) | MKNK1MKNK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107417767-A | Dipeptide compound, its preparation method and the application of piperidines or piperazine structure | 杭州市西溪医院 | 2017-12-01 | — | — | CN | disclosed |