SCHEMBL28198552

SCHEMBL28198552

CC(=O)OCC(=O)N(C)c1c(I)c(C(N)=O)c(I)c(C(N)=O)c1I

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8906457 0.93
SCHEMBL22661231 0.88 MEN1 (0.32) ALDH1A1LMNAHSD17B10
Hydrochloric Acid SCHEMBL11279952 0.86 MEN1 (0.31) ALDH1A1LMNAHSD17B10
SCHEMBL9976307 0.86 ALDH1A1 (0.31) ALDH1A1LMNAHSD17B10
SCHEMBL29234146 0.78 LMNA (0.30) LMNA
SCHEMBL30663537 0.74 LMNA (0.41) LMNA
SCHEMBL9976316 0.72 LMNA (0.46) LMNA
SCHEMBL11275798 0.71 HSD17B10 (0.32) ALDH1A1HSD17B10
SCHEMBL9563838 0.70 BTK (0.31) ALDH1A1
Hydrochloric Acid SCHEMBL8596838 0.70 HSD17B10 (0.31) ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106316878-B A kind of preparation method of iomeprol impurity 重庆常捷医药有限公司 2018-01-19 CN claimed
EP-3854780-B1 METHOD FOR PREPARING CONTRAST AGENT IOMEPROL UK CHEMIPHARM CO LTD (KR) 2023-10-18 EP disclosed
US-11396490-B2 Method for preparing contrast agent iomeprol UK CHEMIPHARM CO., LTD (KR) 2022-07-26 US disclosed
US-20220024857-A1 METHOD FOR PREPARING CONTRAST AGENT IOMEPROL UK CHEMIPHARM CO., LTD (KR) 2022-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220024857-A1 METHOD FOR PREPARING CONTRAST AGENT IOMEPROL PPIP5K2, SLC5A11, INMT ALDH1A1 4045/4885LMNA 2169/4885HSD17B10 4786/4885
US-11396490-B2 Method for preparing contrast agent iomeprol PPIP5K2, SLC5A11, INMT ALDH1A1 4045/4885LMNA 2169/4885HSD17B10 4786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.