SCHEMBL9976307

SCHEMBL9976307

CC(=O)OCC(=O)N(C)c1c(I)c(C(=O)Cl)c(I)c(C(=O)Cl)c1I

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8906457 0.94
SCHEMBL28198552 0.86 ALDH1A1 (0.31) ALDH1A1LMNAHSD17B10
SCHEMBL22661231 0.86 MEN1 (0.32) ALDH1A1LMNAHSD17B10
Hydrochloric Acid SCHEMBL11279952 0.85 MEN1 (0.31) ALDH1A1LMNAHSD17B10
SCHEMBL8596835 0.84 HSD17B10 (0.31) ALDH1A1HSD17B10
SCHEMBL9976316 0.84 LMNA (0.46) LMNA
SCHEMBL9009185 0.79 ALDH1A1 (0.31) ALDH1A1
SCHEMBL9787585 0.76 KDM4E (0.31) ALDH1A1LMNAHSD17B10
SCHEMBL30663537 0.73 LMNA (0.41) LMNA
SCHEMBL11278009 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116354842-A Improved preparation method of iomeprol and application of iomeprol in preparation 重庆圣华曦药业股份有限公司 2023-06-30 CN disclosed
EP-3580199-B1 METHOD FOR THE ONE-POT PRODUCTION OF ORGANO-IODINATED COMPOUNDS GUERBET SA (FR) 2023-04-05 EP disclosed
US-10836711-B2 Method for the one-pot production of organo-iodinated compounds GUERBET (FR) 2020-11-17 US disclosed
US-10836711-B2 Method for the one-pot production of organo-iodinated compounds GUERBET (FR) 2020-11-17 US disclosed
EP-2200656-B1 CONTRAST AGENTS GE HEALTHCARE AS (NO) 2012-12-05 EP disclosed
US-8323619-B2 Contrast agents GE HEALTHCARE AS (NO) 2012-12-04 US disclosed
US-8323619-B2 Contrast agents GE HEALTHCARE AS (NO) 2012-12-04 US disclosed
US-8202511-B2 Contrast agents GE HEALTHCARE AS (NO) 2012-06-19 US disclosed
US-8202511-B2 Contrast agents GE HEALTHCARE AS (NO) 2012-06-19 US disclosed
US-20100303734-A1 CONTRAST AGENTS GE HEALTHCARE AS (NO) 2010-12-02 US disclosed
US-20100303734-A1 CONTRAST AGENTS GE HEALTHCARE AS (NO) 2010-12-02 US disclosed
US-20100233097-A1 CONTRAST AGENTS GE HEALTHCARE AS (NO) 2010-09-16 US disclosed
US-20100233097-A1 CONTRAST AGENTS GE HEALTHCARE AS (NO) 2010-09-16 US disclosed
US-20100221189-A1 CONTRAST AGENTS GE HEALTHCARE AS (NO) 2010-09-02 US disclosed
US-20100221189-A1 CONTRAST AGENTS GE HEALTHCARE AS (NO) 2010-09-02 US disclosed
WO-2009071605-A1 CONTRAST AGENTS GE HEALTHCARE AS (NO) 2009-06-11 WO disclosed
WO-2009060021-A1 CONTRAST AGENTS GE HEALTHCARE AS (NO) 2009-05-14 WO disclosed
WO-2009047319-A1 CONTRAST AGENTS GE HEALTHCARE AS (NO) 2009-04-16 WO disclosed
US-4352788-A ARTERIES BRACCO INDUSTRIA CHIMICA S.P.A. (IT) 1982-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10836711-B2 Method for the one-pot production of organo-iodinated compounds TPO, NISCH, PPIP5K2 ALDH1A1 2138/4885LMNA 3525/4885HSD17B10 2776/4885
US-20100221189-A1 CONTRAST AGENTS NR1I3, NR1I2, NR1D2 ALDH1A1 1588/4885LMNA 2753/4885HSD17B10 1215/4885
US-20100233097-A1 CONTRAST AGENTS C1R, C3AR1, CNKSR1 ALDH1A1 2310/4885LMNA 1939/4885HSD17B10 2016/4885
US-20100303734-A1 CONTRAST AGENTS C1R, CNKSR1, C5 ALDH1A1 2186/4885LMNA 2025/4885HSD17B10 2749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.