Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28201035 | 0.78 | CYP2D6 (0.39) | TSHRMAPK1LMNACYP2A6 | |
| SCHEMBL10951502 | 0.75 | CYP3A4 (0.39) | HSD17B10SLC6A4SLC6A3CYP2C19CYP19A1 | |
| SCHEMBL3633293 | 0.75 | HSD17B10 (0.34) | ADRB2BRD4HSD17B10FFAR2TSHR | |
| SCHEMBL8491351 | 0.74 | TRPA1 (0.43) | HSD17B10TSHRMAPK1TDP1HPGD | |
| SCHEMBL96817 | 0.71 | ADRB2 (0.50) | ADRB2BRD4HSD17B10FFAR2TSHR | |
| SCHEMBL11815736 | 0.71 | ADRB2 (0.50) | ADRB2BRD4HSD17B10FFAR2TSHR | |
| SCHEMBL23580752 | 0.71 | ADRB2 (0.40) | ADRB2BRD4HSD17B10FFAR2TSHR | |
| SCHEMBL1792519 | 0.70 | HSD17B10 (0.46) | ADRB2BRD4HSD17B10FFAR2TSHR | |
| SCHEMBL1978297 | 0.70 | HSD17B10 (0.46) | ADRB2BRD4HSD17B10FFAR2TSHR | |
| SCHEMBL11572011 | 0.70 | SLC6A4 (0.48) | ADRB2BRD4TSHRMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035915-A1 | SULFUR CONTAINING PYRAZOLE-HETEROCYCLE DERIVATIVES AS CANNABINOID CB1 RECEPTOR ANTAGONISTS | GREEN CROSS CORPORATION (KR) | 2010-04-01 | — | — | WO | disclosed |