Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.35 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28200545 | 0.83 | NAALAD2 (0.37) | NAALAD2HTTALDH1A1KDM4EHPGD | |
| SCHEMBL28108424 | 0.75 | FPR2 (0.41) | ALDH1A1TAS1R3TAS1R1KDM4EHPGD | |
| SCHEMBL28108428 | 0.73 | NAALAD2 (0.35) | NAALAD2HTTALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL13446576 | 0.71 | ADORA3 (0.32) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL28108413 | 0.70 | L3MBTL1 (0.41) | ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL28201172 | 0.69 | MME (0.38) | NAALAD2HTTADORA3ADORA2AADORA2B | |
| SCHEMBL1479318 | 0.67 | PLA2G2C (0.55) | NAALAD2PLA2G2CANPEPENPEPKDM4E | |
| SCHEMBL13446570 | 0.67 | — | — | |
| SCHEMBL14121455 | 0.67 | MMEL1 (0.40) | ALDH1A1 | |
| SCHEMBL3503915 | 0.66 | PLA2G2C (0.54) | NAALAD2PLA2G2CANPEPENPEPKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104520277-B | Enkephalinase inhibitors | 施万生物制药研发IP有限责任公司 | 2018-01-19 | — | — | CN | disclosed |