Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.38 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.36 |
| ▸ | MMEL1 | Q495T6 | 3/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | GRN | P28799 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28200545 | 0.80 | NAALAD2 (0.37) | NAALAD2ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL28108424 | 0.74 | FPR2 (0.41) | MMEFOLH1HCAR3GRNSORT1 | |
| SCHEMBL13446576 | 0.74 | ADORA3 (0.32) | ADORA3ADORA2AADORA2BADORA1HCAR3 | |
| SCHEMBL28108413 | 0.72 | L3MBTL1 (0.41) | KMT2AL3MBTL1POLB | |
| SCHEMBL28108429 | 0.71 | MMEL1 (0.37) | MMENAALAD2FOLH1MMEL1GRN | |
| SCHEMBL28201169 | 0.69 | NAALAD2 (0.35) | NAALAD2ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL30568662 | 0.69 | — | — | |
| SCHEMBL13446570 | 0.69 | — | — | |
| SCHEMBL25060915 | 0.67 | — | — | |
| SCHEMBL15997875 | 0.66 | KDM4E (0.44) | MMENAALAD2FOLH1MMEL1GRN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104520277-B | Enkephalinase inhibitors | 施万生物制药研发IP有限责任公司 | 2018-01-19 | — | — | CN | disclosed |