Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 5/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | DRD3 | P35462 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28201595 | 0.78 | L3MBTL1 (0.36) | LMNAKDM4EADRA2BADRA2CADRA2A | |
| SCHEMBL28201586 | 0.77 | CYP2A6 (0.36) | HRH1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL19142282 | 0.72 | CYP11B1 (0.36) | HRH1CHRM2CHRM1DRD2DRD3 | |
| SCHEMBL4340785 | 0.70 | TSHR (0.32) | HRH1CHRM2CHRM1DRD2LMNA | |
| SCHEMBL28857380 | 0.70 | HRH1 (0.34) | HRH1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28276888 | 0.68 | CYP11B2 (0.33) | HRH1CHRM2CHRM1DRD2MAPT | |
| SCHEMBL28202178 | 0.68 | HDAC8 (0.32) | HRH1CHRM2CHRM1DRD2TSHR | |
| SCHEMBL28195678 | 0.68 | HDAC1 (0.32) | HRH1CHRM2CHRM1DRD2TSHR | |
| SCHEMBL28201612 | 0.68 | NPC1 (0.33) | HRH1CHRM2CHRM1DRD2KDM4E | |
| SCHEMBL28201589 | 0.65 | CHRM2 (0.30) | HRH1CHRM2CHRM1DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105683188-B | The ring pyridinyl derivatives of condensed ring two as FGFR4 inhibitor | 诺华股份有限公司 | 2018-02-09 | — | — | CN | disclosed |